Revealing low-dose radiation damage using single-crystal spectroscopy

by Owen, Robin L., Yorke, Briony A., Gowdy, James A., Pearson, Arwen R.
Published 2011

Probing the Molecular Mechanisms in Copper Amine Oxidases by Generating Heterodimers

by Gaule, Thembaninkosi G, Smith, Mark A, Pearson, Arwen R, Knowles, Peter F, McPherson, Michael J
Published 2015

Time-resolved crystallography using the Hadamard Transform

by Yorke, Briony A., Beddard, Godfrey S., Owen, Robin L., Pearson, Arwen R.
Published 2014

Structural Insights into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical...

by Timms, Nicole, Windle, Claire L, Polyakova, Anna, Ault, James R, Trinh, Chi H, Pearson, Arwen R, Nelson, Adam, Berry, Alan
Published 2013

Limits of Structural Plasticity in a Picornavirus Capsid Revealed by a Massively Expanded Equine Rhinitis A Virus Particle

by Bakker, Saskia E., Groppelli, Elisabetta, Pearson, Arwen R., Stockley, Peter G., Rowlands, David J., Ranson, Neil A.
Published 2014

Threonine 57 is required for the post-translational activation of Escherichia coli aspartate α-decarboxylase

by Webb, Michael E., Yorke, Briony A., Kershaw, Tom, Lovelock, Sarah, Lobley, Carina M. C., Kilkenny, Mairi L., Smith, Alison G., Blundell, Tom L., Pearson, Arwen R., Abell, Chris
Published 2014

Sequence-Specific, RNA–Protein Interactions Overcome Electrostatic Barriers Preventing Assembly of Satellite Tobacco Necrosis Virus Coat Protein

by Ford, Robert J., Barker, Amy M., Bakker, Saskia E., Coutts, Robert H., Ranson, Neil A., Phillips, Simon E.V., Pearson, Arwen R., Stockley, Peter G.
Published 2013

Evaluation of fluoropyruvate as nucleophile in reactions catalysed by N-acetyl neuraminic acid lyase variants: scope, limitations and stereoselectivity† †Electronic supplementary i...

by Stockwell, Jennifer, Daniels, Adam D., Windle, Claire L., Harman, Thomas A., Woodhall, Thomas, Lebl, Tomas, Trinh, Chi H., Mulholland, Keith, Pearson, Arwen R., Berry, Alan, Nelson, Adam
Published 2016

Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus

by Bakker, Saskia E., Ford, Robert J., Barker, Amy M., Robottom, Janice, Saunders, Keith, Pearson, Arwen R., Ranson, Neil A., Stockley, Peter G.
Published 2012

In pursuit of an accurate spatial and temporal model of biomolecules at the atomistic level: a perspective on computer simulation

by Gray, Alan, Harlen, Oliver G., Harris, Sarah A., Khalid, Syma, Leung, Yuk Ming, Lonsdale, Richard, Mulholland, Adrian J., Pearson, Arwen R., Read, Daniel J., Richardson, Robin A.
Published 2015

Packaging signals in single-stranded RNA viruses: nature’s alternative to a purely electrostatic assembly mechanism

by Stockley, Peter G., Twarock, Reidun, Bakker, Saskia E., Barker, Amy M., Borodavka, Alexander, Dykeman, Eric, Ford, Robert J., Pearson, Arwen R., Phillips, Simon E. V., Ranson, Neil A., Tuma, Roman
Published 2013

Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis

by Daniels, Adam D., Campeotto, Ivan, van der Kamp, Marc W., Bolt, Amanda H., Trinh, Chi H., Phillips, Simon E. V., Pearson, Arwen R., Nelson, Adam, Mulholland, Adrian J., Berry, Alan
Published 2014

The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A

by Monteiro, Diana C.F., Patel, Vijay, Bartlett, Christopher P., Nozaki, Shingo, Grant, Thomas D., Gowdy, James A., Thompson, Gary S., Kalverda, Arnout P., Snell, Edward H., Niki, Hironori, Pearson, Arwen R., Webb, Michael E.
Published 2015

Structure-Guided Design Affirms Inhibitors of Hepatitis C Virus p7 as a Viable Class of Antivirals Targeting Virion Release

by Foster, Toshana L, Thompson, Gary S, Kalverda, Arnout P, Kankanala, Jayakanth, Bentham, Matthew, Wetherill, Laura F, Thompson, Joseph, Barker, Amy M, Clarke, Dean, Noerenberg, Marko, Pearson, Arwen R, Rowlands, David J, Homans, Steven W, Harris, Mark, Foster, Richard, Griffin, Stephen
Published 2014