Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose

by Li, Jingjing, Li, Sijia, Zhang, Lan, Ouyang, Liang, Liu, Bo
Published 2015

Combined Structure-Based Pharmacophore and 3D-QSAR Studies on Phenylalanine Series Compounds as TPH1 Inhibitors

by Ouyang, Liang, He, Gu, Huang, Wei, Song, Xiangrong, Wu, Fengbo, Xiang, Mingli
Published 2012

Discovery of Novel Focal Adhesion Kinase Inhibitors Using a Hybrid Protocol of Virtual Screening Approach Based on Multicomplex-Based Pharmacophore and Molecular Docking

by Wu, Fengbo, Xu, Ting, He, Gu, Ouyang, Liang, Han, Bo, Peng, Cheng, Song, Xiangrong, Xiang, Mingli
Published 2012

Molecular Dynamics Simulation of Tryptophan Hydroxylase-1: Binding Modes and Free Energy Analysis to Phenylalanine Derivative Inhibitors

by Zhong, Hao, Huang, Wei, He, Gu, Peng, Cheng, Wu, Fengbo, Ouyang, Liang
Published 2013

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer

by Liu, Bo, Fu, Leilei, Zhang, Cui, Zhang, Lan, Zhang, Yonghui, Ouyang, Liang, He, Gu, Huang, Jian
Published 2015

CTLPScanner: a web server for chromothripsis-like pattern detection

by Yang, Jian, Liu, Jixiang, Ouyang, Liang, Chen, Yi, Liu, Bo, Cai, Haoyang
Published 2016

ACTP: A webserver for predicting potential targets and relevant pathways of autophagy-modulating compounds

by Xie, Tao, Zhang, Lan, Zhang, Shouyue, Ouyang, Liang, Cai, Haoyang, Liu, Bo
Published 2016

Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery

by Fu, Lei-lei, Tian, Mao, Li, Xiang, Li, Jing-jing, Huang, Jian, Ouyang, Liang, Zhang, Yonghui, Liu, Bo
Published 2015

Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

by Fu, Leilei, Zhang, Shouyue, Zhang, Lan, Tong, Xupeng, Zhang, Jin, Zhang, Yonghui, Ouyang, Liang, Liu, Bo, Huang, Jian
Published 2015

Identification of ULK1 as a novel biomarker involved in miR-4487 and miR-595 regulation in neuroblastoma SH-SY5Y cell autophagy

by Chen, Yi, Wang, Shuya, Zhang, Lan, Xie, Tao, Song, Sicheng, Huang, Jian, Zhang, Yonghui, Ouyang, Liang, Liu, Bo
Published 2015

CEMTDD: The database for elucidating the relationships among herbs, compounds, targets and related diseases for Chinese ethnic minority traditional drugs

by Huang, Jian, Zheng, Yaxin, Wu, Wenxi, Xie, Tao, Yao, Hong, Pang, Xiaobo, Sun, Fuzhou, Ouyang, Liang, Wang, Jinhui
Published 2015

Discovery and in Vivo Evaluation of Novel RGD-Modified Lipid-Polymer Hybrid Nanoparticles for Targeted Drug Delivery

by Zhao, Yinbo, Lin, Dayong, Wu, Fengbo, Guo, Li, He, Gu, Ouyang, Liang, Song, Xiangrong, Huang, Wei, Li, Xiang
Published 2014

Combining structure-based pharmacophore modeling, virtual screening, and in silico ADMET analysis to discover novel tetrahydro-quinoline based pyruvate kinase isozyme M2 activators...

by Chen, Can, Wang, Ting, Wu, Fengbo, Huang, Wei, He, Gu, Ouyang, Liang, Xiang, Mingli, Peng, Cheng, Jiang, Qinglin
Published 2014