Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/h...

by Machwe, Amrita, Xiao, Liren, Orren, David K
Published 2006

Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins

by Machwe, Amrita, Lozada, Enerlyn M, Xiao, Liren, Orren, David K
Published 2006

Intramolecular Telomeric G-Quadruplexes Dramatically Inhibit DNA Synthesis by Replicative and Translesion Polymerases, Revealing their Potential to Lead to Genetic Change

by Edwards, Deanna N., Machwe, Amrita, Wang, Zhigang, Orren, David K.
Published 2014

Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2

by Edwards, Deanna N., Orren, David K., Machwe, Amrita
Published 2014

Replication fork regression in vitro by the Werner syndrome protein (WRN): Holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease...

by Machwe, Amrita, Xiao, Liren, Lloyd, Robert G., Bolt, Edward, Orren, David K.
Published 2007

The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events

by Edwards, Deanna N., Machwe, Amrita, Chen, Li, Bohr, Vilhelm A., Orren, David K.
Published 2015

Exposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pathway

by Holcomb, Nathaniel, Goswami, Mamta, Han, Sung Gu, Clark, Samuel, Orren, David K., Gairola, C. Gary, Mellon, Isabel
Published 2016