Dynamic Changes of the Phosphoproteome in Postmortem Mouse Brains

by Oka, Tsutomu, Tagawa, Kazuhiko, Ito, Hikaru, Okazawa, Hitoshi
Published 2011

Fasting activates macroautophagy in neurons of Alzheimer’s disease mouse model but is insufficient to degrade amyloid-beta

by Chen, Xigui, Kondo, Kanoh, Motoki, Kazumi, Homma, Hidenori, Okazawa, Hitoshi
Published 2015

Systematic Analysis of Fly Models with Multiple Drivers Reveals Different Effects of Ataxin-1 and Huntingtin in Neuron Subtype-Specific Expression

by Shiraishi, Risa, Tamura, Takuya, Sone, Masaki, Okazawa, Hitoshi
Published 2014

Correction: Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease

by Tamura, Takuya, Sone, Masaki, Iwatsubo, Takeshi, Tagawa, Kazuhiko, Wanker, Erich E., Okazawa, Hitoshi
Published 2012

Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease

by Tamura, Takuya, Sone, Masaki, Iwatsubo, Takeshi, Tagawa, Kazuhiko, Wanker, Erich E., Okazawa, Hitoshi
Published 2011

Sox2 Transcriptionally Regulates Pqbp1, an Intellectual Disability-Microcephaly Causative Gene, in Neural Stem Progenitor Cells

by Li, Chan, Ito, Hikaru, Fujita, Kyota, Shiwaku, Hiroki, Qi, Yunlong, Tagawa, Kazuhiko, Tamura, Takuya, Okazawa, Hitoshi
Published 2013

HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice

by Ito, Hikaru, Fujita, Kyota, Tagawa, Kazuhiko, Chen, Xigui, Homma, Hidenori, Sasabe, Toshikazu, Shimizu, Jun, Shimizu, Shigeomi, Tamura, Takuya, Muramatsu, Shin-ichi, Okazawa, Hitoshi
Published 2015

Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73

by Hoshino, Masataka, Qi, Mei-ling, Yoshimura, Natsue, Miyashita, Tomoyuki, Tagawa, Kazuhiko, Wada, Yo-ichi, Enokido, Yasushi, Marubuchi, Shigeki, Harjes, Phoebe, Arai, Nobutaka, Oyanagi, Kiyomitsu, Blandino, Giovanni, Sudol, Marius, Rich, Tina, Kanazawa, Ichiro, Wanker, Erich E., Saitoe, Minoru, Okazawa, Hitoshi
Published 2006

Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro- in vivo-integrated screens of chemical libraries

by Imamura, Tomomi, Fujita, Kyota, Tagawa, Kazuhiko, Ikura, Teikichi, Chen, Xigui, Homma, Hidenori, Tamura, Takuya, Mao, Ying, Taniguchi, Juliana Bosso, Motoki, Kazumi, Nakabayashi, Makoto, Ito, Nobutoshi, Yamada, Kazunori, Tomii, Kentaro, Okano, Hideyuki, Kaye, Julia, Finkbeiner, Steven, Okazawa, Hitoshi
Published 2016

HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease

by Fujita, Kyota, Motoki, Kazumi, Tagawa, Kazuhiko, Chen, Xigui, Hama, Hiroshi, Nakajima, Kazuyuki, Homma, Hidenori, Tamura, Takuya, Watanabe, Hirohisa, Katsuno, Masahisa, Matsumi, Chiemi, Kajikawa, Masunori, Saito, Takashi, Saido, Takaomi, Sobue, Gen, Miyawaki, Atsushi, Okazawa, Hitoshi
Published 2016