Summit on cell therapy for cancer: The importance of the interaction of multiple disciplines to advance clinical therapy

by Melief, Cornelis JM, O'Shea, John J, Stroncek, David F
Published 2011

Helper T cell differentiation enters a new era: Le Roi est mort; vive le Roi!

by Tato, Cristina M., Laurence, Arian, O'Shea, John J.
Published 2006

Kinase inhibitors in the treatment of immune-mediated disease

by Kontzias, Apostolos, Laurence, Arian, Gadina, Massimo, O’Shea, John J.
Published 2012

IL-27 shakes up the establishment of ectopic lymphoid structures

by Villarino, Alejandro V., O’Shea, John J., Hunter, Christopher A.
Published 2015

The Janus kinases (Jaks)

by Yamaoka, Kunihiro, Saharinen, Pipsa, Pesu, Marko, Holt, Vance ET, Silvennoinen, Olli, O'Shea, John J
Published 2004

Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation

by Ortmann, Robert A, Cheng, Tammy, Visconti, Roberta, Frucht , David M, O'Shea, John J
Published 2000

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

by Usui, Takashi, Preiss, Jan C., Kanno, Yuka, Yao, Zheng Ju, Bream, Jay H., O'Shea, John J., Strober, Warren
Published 2006

Title not available

by Usui, Takashi, Preiss, Jan C., Kanno, Yuka, Yao, Zheng Ju, Bream, Jay H., O'Shea, John J., Strober, Warren
Published 2006

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals

by Villarino, Alejandro V., Tato, Cristina M., Stumhofer, Jason S., Yao, Zhengju, Cui, Yongzhi K., Hennighausen, Lothar, O'Shea, John J., Hunter, Christopher A.
Published 2007

Tissue Inhibitor of Metalloproteinase 1 Is Preferentially Expressed in Th1 and Th17 T-Helper Cell Subsets and Is a Direct Stat Target Gene

by Adamson, Adewole, Ghoreschi, Kamran, Rittler, Matthew, Chen, Qian, Sun, Hong-Wei, Vahedi, Golnaz, Kanno, Yuka, Stetler-Stevenson, William G., O’Shea, John J., Laurence, Arian
Published 2013

Reversal of CD8 T-Cell–Mediated Mucocutaneous Graft-Versus-Host-Like Disease by the JAK Inhibitor Tofacitinib

by Okiyama, Naoko, Furumoto, Yasuko, Villarroel, Vadim A, Linton, Jay T, Tsai, Wanxia L, Gutermuth, Jan, Ghoreschi, Kamran, Gadina, Massimo, O'Shea, John J, Katz, Stephen I
Published 2014

Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ

by Astry, Brian, Venkatesha, Shivaprasad H., Laurence, Arian, Christensen-Quick, Aaron, Garzinodemo, Alfredo, Frieman, Matthew B, O’Shea, John J., Moudgil, Kamal D.
Published 2015

An autoregulatory enhancer controls mammary-specific STAT5 functions

by Metser, Gil, Shin, Ha Youn, Wang, Chaochen, Yoo, Kyung Hyun, Oh, Sumin, Villarino, Alejandro V., O'Shea, John J., Kang, Keunsoo, Hennighausen, Lothar
Published 2016

PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond

by Bible, Paul W., Kanno, Yuka, Wei, Lai, Brooks, Stephen R., O’Shea, John J., Morasso, Maria I., Loganantharaj, Rasiah, Sun, Hong-Wei
Published 2015

Distinct requirements for T-bet in gut innate lymphoid cells

by Sciumé, Giuseppe, Hirahara, Kiyoshi, Takahashi, Hayato, Laurence, Arian, Villarino, Alejandro V., Singleton, Kentner L., Spencer, Sean P., Wilhelm, Christoph, Poholek, Amanda C., Vahedi, Golnaz, Kanno, Yuka, Belkaid, Yasmine, O'Shea, John J.
Published 2012

Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells

by Vahedi, Golnaz, Kanno, Yuka, Furumoto, Yasuko, Jiang, Kan, Parker, Stephen C., Erdos, Michael, Davis, Sean R., Roychoudhuri, Rahul, Restifo, Nicholas P., Gadina, Massimo, Tang, Zhonghui, Ruan, Yijun, Collins, Francis S., Sartorelli, Vittorio, O’Shea, John J.
Published 2015

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions

by Villarino, Alejandro, Laurence, Arian, Robinson, Gertraud W, Bonelli, Michael, Dema, Barbara, Afzali, Behdad, Shih, Han-Yu, Sun, Hong-Wei, Brooks, Stephen R, Hennighausen, Lothar, Kanno, Yuka, O'Shea, John J
Published 2016

Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia

by Zhang, Meili, Griner, Lesley A Mathews, Ju, Wei, Duveau, Damien Y, Guha, Rajarshi, Petrus, Michael, Wen, Bernard, Maeda, Michiyuki, Shinn, Paul, Ferrer, Marc, Conlon, Kevin C, Bamford, Richard, O'Shea, John J, Thomas, Craig J, Waldmann, Thomas A
Published 2015

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion

by Yang, Xiang-Ping, Jiang, Kan, Hirahara, Kiyoshi, Vahedi, Golnaz, Afzali, Behdad, Sciume, Giuseppe, Bonelli, Michael, Sun, Hong-Wei, Jankovic, Dragana, Kanno, Yuka, Sartorelli, Vittorio, O’Shea, John J., Laurence, Arian
Published 2015

Generation of Pathogenic Th17 Cells in the Absence of TGF-β Signaling

by Ghoreschi, Kamran, Laurence, Arian, Yang, Xiang-Ping, Tato, Cristina M., McGeachy, Mandy J., Konkel, Joanne, Ramos, Haydeé L., Wei, Lai, Davidson, Todd, Bouladoux, Nicolas, Grainger, John, Chen, Qian, Kanno, Yuka, Watford, Wendy T., Sun, Hong-Wei, Eberl, Gérard, Shevach, Ethan, Belkaid, Yasmine, Cua, Daniel J., Chen, Wanjun, O’Shea, John J.
Published 2010