Mouse models of medulloblastoma

by Wu, Xiaochong, Northcott, Paul A., Croul, Sidney, Taylor, Michael D.
Published 2011

The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

by Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Published 2014

Molecular subgroups of medulloblastoma: the current consensus

by Taylor, Michael D., Northcott, Paul A., Korshunov, Andrey, Remke, Marc, Cho, Yoon-Jae, Clifford, Steven C., Eberhart, Charles G., Parsons, D. Williams, Rutkowski, Stefan, Gajjar, Amar, Ellison, David W., Lichter, Peter, Gilbertson, Richard J., Pomeroy, Scott L., Kool, Marcel, Pfister, Stefan M.
Published 2011

Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

by Northcott, Paul A., Shih, David J. H., Remke, Marc, Cho, Yoon-Jae, Kool, Marcel, Hawkins, Cynthia, Eberhart, Charles G., Dubuc, Adrian, Guettouche, Toumy, Cardentey, Yoslayma, Bouffet, Eric, Pomeroy, Scott L., Marra, Marco, Malkin, David, Rutka, James T., Korshunov, Andrey, Pfister, Stefan, Taylor, Michael D.
Published 2011

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

by Hovestadt, Volker, Remke, Marc, Kool, Marcel, Pietsch, Torsten, Northcott, Paul A., Fischer, Roger, Cavalli, Florence M. G., Ramaswamy, Vijay, Zapatka, Marc, Reifenberger, Guido, Rutkowski, Stefan, Schick, Matthias, Bewerunge-Hudler, Melanie, Korshunov, Andrey, Lichter, Peter, Taylor, Michael D., Pfister, Stefan M., Jones, David T. W.
Published 2013

LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)

by Korshunov, Andrey, Ryzhova, Marina, Jones, David T. W., Northcott, Paul A., van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, Cowdrey, Cynthia, Perry, Arie, Picard, Daniel, Rosenblum, Marc, Giangaspero, Felice, Aronica, Eleonora, Schüller, Ulrich, Hasselblatt, Martin, Collins, V. Peter, von Deimling, Andreas, Lichter, Peter, Huang, Annie, Pfister, Stefan M., Kool, Marcel
Published 2012

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing

by Jäger, Natalie, Jones, David TW, Kool, Marcel, Zichner, Thomas, Hutter, Barbara, Sultan, Marc, Cho, Yoon-Jae, Pugh, Trevor J, Hovestadt, Volker, Stütz, Adrian M, Rausch, Tobias, Warnatz, Hans-Jörg, Brors, Benedikt, Northcott, Paul A, Taylor, Michael D, Meyerson, Matthew, Pomeroy, Scott L, Yaspo, Marie-Laure, Korbel, Jan O, Korshunov, Andrey, Eils, Roland, Pfister, Stefan M, Lichter, Peter
Published 2012

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

by Pietsch, Torsten, Schmidt, Rene, Remke, Marc, Korshunov, Andrey, Hovestadt, Volker, Jones, David T. W., Felsberg, Jörg, Kaulich, Kerstin, Goschzik, Tobias, Kool, Marcel, Northcott, Paul A., von Hoff, Katja, von Bueren, André O., Friedrich, Carsten, Mynarek, Martin, Skladny, Heyko, Fleischhack, Gudrun, Taylor, Michael D., Cremer, Friedrich, Lichter, Peter, Faldum, Andreas, Reifenberger, Guido, Rutkowski, Stefan, Pfister, Stefan M.
Published 2014

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

by Zuckermann, Marc, Hovestadt, Volker, Knobbe-Thomsen, Christiane B., Zapatka, Marc, Northcott, Paul A., Schramm, Kathrin, Belic, Jelena, Jones, David T. W., Tschida, Barbara, Moriarity, Branden, Largaespada, David, Roussel, Martine F., Korshunov, Andrey, Reifenberger, Guido, Pfister, Stefan M., Lichter, Peter, Kawauchi, Daisuke, Gronych, Jan
Published 2015

Proteomic profiling of high risk medulloblastoma reveals functional biology

by Staal, Jerome A., Lau, Ling San, Zhang, Huizhen, Ingram, Wendy J., Hallahan, Andrew R., Northcott, Paul A., Pfister, Stefan M., Wechsler-Reya, Robert J., Rusert, Jessica M., Taylor, Michael D., Cho, Yoon-Jae, Packer, Roger J., Brown, Kristy J., Rood, Brian R.
Published 2015

Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation

by Bassett, Erin A, Tokarew, Nicholas, Allemano, Ema A, Mazerolle, Chantal, Morin, Katy, Mears, Alan J, McNeill, Brian, Ringuette, Randy, Campbell, Charles, Smiley, Sheila, Pokrajac, Neno T, Dubuc, Adrian M, Ramaswamy, Vijay, Northcott, Paul A, Remke, Marc, Monnier, Philippe P, Potter, David, Paes, Kim, Kirkpatrick, Laura L, Coker, Kenneth J, Rice, Dennis S, Perez-Iratxeta, Carol, Taylor, Michael D, Wallace, Valerie A
Published 2016

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

by Kool, Marcel, Korshunov, Andrey, Remke, Marc, Jones, David T. W., Schlanstein, Maria, Northcott, Paul A., Cho, Yoon-Jae, Koster, Jan, Schouten-van Meeteren, Antoinette, van Vuurden, Dannis, Clifford, Steven C., Pietsch, Torsten, von Bueren, Andre O., Rutkowski, Stefan, McCabe, Martin, Collins, V. Peter, Bäcklund, Magnus L., Haberler, Christine, Bourdeaut, Franck, Delattre, Olivier, Doz, Francois, Ellison, David W., Gilbertson, Richard J., Pomeroy, Scott L., Taylor, Michael D., Lichter, Peter, Pfister, Stefan M.
Published 2012

Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

by Jäger, Natalie, Schlesner, Matthias, Jones, David T.W., Raffel, Simon, Mallm, Jan-Philipp, Junge, Kristin M., Weichenhan, Dieter, Bauer, Tobias, Ishaque, Naveed, Kool, Marcel, Northcott, Paul A., Korshunov, Andrey, Drews, Ruben M., Koster, Jan, Versteeg, Rogier, Richter, Julia, Hummel, Michael, Mack, Stephen C., Taylor, Michael D., Witt, Hendrik, Swartman, Benedict, Schulte-Bockholt, Dietrich, Sultan, Marc, Yaspo, Marie-Laure, Lehrach, Hans, Hutter, Barbara, Brors, Benedikt, Wolf, Stephan, Plass, Christoph, Siebert, Reiner, Trumpp, Andreas, Rippe, Karsten, Lehmann, Irina, Lichter, Peter, Pfister, Stefan M., Eils, Roland
Published 2013

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

by Oh, Sekyung, Flynn, Ryan A., Floor, Stephen N., Purzner, James, Martin, Lance, Do, Brian T., Schubert, Simone, Vaka, Dedeepya, Morrissy, Sorana, Li, Yisu, Kool, Marcel, Hovestadt, Volker, Jones, David T.W., Northcott, Paul A., Risch, Thomas, Warnatz, Hans-Jörg, Yaspo, Marie-Laure, Adams, Christopher M., Leib, Ryan D., Breese, Marcus, Marra, Marco A., Malkin, David, Lichter, Peter, Doudna, Jennifer A., Pfister, Stefan M., Taylor, Michael D., Chang, Howard Y., Cho, Yoon-Jae
Published 2016

MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS

by Pugh, Trevor J., Weeraratne, Shyamal Dilhan, Archer, Tenley C., Pomeranz Krummel, Daniel A., Auclair, Daniel, Bochicchio, James, Carneiro, Mauricio O., Carter, Scott L., Cibulskis, Kristian, Erlich, Rachel L., Greulich, Heidi, Lawrence, Michael S., Lennon, Niall J., McKenna, Aaron, Meldrim, James, Ramos, Alex H., Ross, Michael G., Russ, Carsten, Shefler, Erica, Sivachenko, Andrey, Sogoloff, Brian, Stojanov, Petar, Tamayo, Pablo, Mesirov, Jill P., Amani, Vladimir, Teider, Natalia, Sengupta, Soma, Francois, Jessica Pierre, Northcott, Paul A., Taylor, Michael D., Yu, Furong, Crabtree, Gerald R., Kautzman, Amanda G., Gabriel, Stacey B., Getz, Gad, Jäger, Natalie, Jones, David T. W., Lichter, Peter, Pfister, Stefan M., Roberts, Thomas M., Meyerson, Matthew, Pomeroy, Scott L., Cho, Yoon-Jae
Published 2012

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group

by Gottardo, Nicholas G., Hansford, Jordan R., McGlade, Jacqueline P., Alvaro, Frank, Ashley, David M., Bailey, Simon, Baker, David L., Bourdeaut, Franck, Cho, Yoon-Jae, Clay, Moira, Clifford, Steven C., Cohn, Richard J., Cole, Catherine H., Dallas, Peter B., Downie, Peter, Doz, François, Ellison, David W., Endersby, Raelene, Fisher, Paul G., Hassall, Timothy, Heath, John A., Hii, Hilary L., Jones, David T. W., Junckerstorff, Reimar, Kellie, Stewart, Kool, Marcel, Kotecha, Rishi S., Lichter, Peter, Laughton, Stephen J., Lee, Sharon, McCowage, Geoff, Northcott, Paul A., Olson, James M., Packer, Roger J., Pfister, Stefan M., Pietsch, Torsten, Pizer, Barry, Pomeroy, Scott L., Remke, Marc, Robinson, Giles W., Rutkowski, Stefan, Schoep, Tobias, Shelat, Anang A., Stewart, Clinton F., Sullivan, Michael, Taylor, Michael D., Wainwright, Brandon, Walwyn, Thomas, Weiss, William A., Williamson, Dan, Gajjar, Amar
Published 2013

WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma

by Zhukova, Nataliya, Ramaswamy, Vijay, Remke, Marc, Martin, Dianna C, Castelo-Branco, Pedro, Zhang, Cindy H, Fraser, Michael, Tse, Ken, Poon, Raymond, Shih, David JH, Baskin, Berivan, Ray, Peter N, Bouffet, Eric, Dirks, Peter, von Bueren, Andre O, Pfaff, Elke, Korshunov, Andrey, Jones, David TW, Northcott, Paul A, Kool, Marcel, Pugh, Trevor J, Pomeroy, Scott L, Cho, Yoon-Jae, Pietsch, Torsten, Gessi, Marco, Rutkowski, Stefan, Bognár, Laszlo, Cho, Byung-Kyu, Eberhart, Charles G, Conter, Cecile Faure, Fouladi, Maryam, French, Pim J, Grajkowska, Wieslawa A, Gupta, Nalin, Hauser, Peter, Jabado, Nada, Vasiljevic, Alexandre, Jung, Shin, Kim, Seung-Ki, Klekner, Almos, Kumabe, Toshihiro, Lach, Boleslaw, Leonard, Jeffrey R, Liau, Linda M, Massimi, Luca, Pollack, Ian F, Ra, Young Shin, Rubin, Joshua B, Van Meir, Erwin G, Wang, Kyu-Chang, Weiss, William A, Zitterbart, Karel, Bristow, Robert G, Alman, Benjamin, Hawkins, Cynthia E, Malkin, David, Clifford, Steven C, Pfister, Stefan M, Taylor, Michael D, Tabori, Uri
Published 2014

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

by Remke, Marc, Ramaswamy, Vijay, Peacock, John, Shih, David J. H., Koelsche, Christian, Northcott, Paul A., Hill, Nadia, Cavalli, Florence M. G., Kool, Marcel, Wang, Xin, Mack, Stephen C., Barszczyk, Mark, Morrissy, A. Sorana, Wu, Xiaochong, Agnihotri, Sameer, Luu, Betty, Jones, David T. W., Garzia, Livia, Dubuc, Adrian M., Zhukova, Nataliya, Vanner, Robert, Kros, Johan M., French, Pim J., Van Meir, Erwin G., Vibhakar, Rajeev, Zitterbart, Karel, Chan, Jennifer A., Bognár, László, Klekner, Almos, Lach, Boleslaw, Jung, Shin, Saad, Ali G., Liau, Linda M., Albrecht, Steffen, Zollo, Massimo, Cooper, Michael K., Thompson, Reid C., Delattre, Oliver O., Bourdeaut, Franck, Doz, François F., Garami, Miklós, Hauser, Peter, Carlotti, Carlos G., Van Meter, Timothy E., Massimi, Luca, Fults, Daniel, Pomeroy, Scott L., Kumabe, Toshiro, Ra, Young Shin, Leonard, Jeffrey R., Elbabaa, Samer K., Mora, Jaume, Rubin, Joshua B., Cho, Yoon-Jae, McLendon, Roger E., Bigner, Darell D., Eberhart, Charles G., Fouladi, Maryam, Wechsler-Reya, Robert J., Faria, Claudia C., Croul, Sidney E., Huang, Annie, Bouffet, Eric, Hawkins, Cynthia E., Dirks, Peter B., Weiss, William A., Schüller, Ulrich, Pollack, Ian F., Rutkowski, Stefan, Meyronet, David, Jouvet, Anne, Fèvre-Montange, Michelle, Jabado, Nada, Perek-Polnik, Marta, Grajkowska, Wieslawa A., Kim, Seung-Ki, Rutka, James T., Malkin, David, Tabori, Uri, Pfister, Stefan M., Korshunov, Andrey, von Deimling, Andreas, Taylor, Michael D.
Published 2013

Signatures of mutational processes in human cancer

by Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Aparicio, Samuel A.J.R., Behjati, Sam, Biankin, Andrew V., Bignell, Graham R., Bolli, Niccolo, Borg, Ake, Børresen-Dale, Anne-Lise, Boyault, Sandrine, Burkhardt, Birgit, Butler, Adam P., Caldas, Carlos, Davies, Helen R., Desmedt, Christine, Eils, Roland, Eyfjörd, Jórunn Erla, Foekens, John A., Greaves, Mel, Hosoda, Fumie, Hutter, Barbara, Ilicic, Tomislav, Imbeaud, Sandrine, Imielinsk, Marcin, Jäger, Natalie, Jones, David T.W., Jones, David, Knappskog, Stian, Kool, Marcel, Lakhani, Sunil R., López-Otín, Carlos, Martin, Sancha, Munshi, Nikhil C., Nakamura, Hiromi, Northcott, Paul A., Pajic, Marina, Papaemmanuil, Elli, Paradiso, Angelo, Pearson, John V., Puente, Xose S., Raine, Keiran, Ramakrishna, Manasa, Richardson, Andrea L., Richter, Julia, Rosenstiel, Philip, Schlesner, Matthias, Schumacher, Ton N., Span, Paul N., Teague, Jon W., Totoki, Yasushi, Tutt, Andrew N.J., Valdés-Mas, Rafael, van Buuren, Marit M., van ’t Veer, Laura, Vincent-Salomon, Anne, Waddell, Nicola, Yates, Lucy R., Zucman-Rossi, Jessica, Futreal, P. Andrew, McDermott, Ultan, Lichter, Peter, Meyerson, Matthew, Grimmond, Sean M., Siebert, Reiner, Campo, Elías, Shibata, Tatsuhiro, Pfister, Stefan M., Campbell, Peter J., Stratton, Michael R.
Published 2013

Prognostic Value of Medulloblastoma Extent of Resection After Accounting for Molecular Subgroup: An Integrated Clinical and Molecular Analysis

by Thompson, Eric M, Hielscher, Thomas, Bouffet, Eric, Remke, Marc, Luu, Betty, Gururangan, Sridharan, McLendon, Roger E, Bigner, Darell D, Lipp, Eric S, Perreault, Sebastien, Cho, Yoon-Jae, Grant, Gerald, Kim, Seung-Ki, Lee, Seung-Ki Kim Ji Yeoun, Rao, Amulya A Nageswara, Giannini, Caterina, Li, Kay Ka Wai, Ng, Ho-Keung, Yao, Yu, Kumabe, Toshihiro, Tominaga, Teiji, Grajkowska, Wieslawa A, Perek-Polnik, Marta, Low, David CY, Seow, Wan Tew, Chang, Kenneth TE, Mora, Jaume, Pollack, Ian F, Hamilton, Ronald L, Leary, Sarah, Moore, Andrew S., Ingram, Wendy J., Hallahan, Andrew R., Jouvet, Anne, Fèvre-Montange, Michelle, Vasiljevic, Alexandre, Faure-Conter, Cecile, Shofuda, Tomoko, Kagawa, Naoki, Hashimoto, Naoya, Jabado, Nada, Weil, Alexander G, Gayden, Tenzin, Wataya, Takafumi, Shalaby, Tarek, Grotzer, Michael, Zitterbart, Karel, Sterba, Jaroslav, Kren, Leos, Hortobágyi, Tibor, Klekner, Almos, László, Bognár, Pócza, Tímea, Hauser, Peter, Schüller, Ulrich, Jung, Shin, Jang, Woo-Youl, French, Pim J, Kros, Johan M, van Veelen, Marie-Lise C, Massimi, Luca, Leonard, Jeffrey R, Rubin, Joshua B, Vibhakar, Rajeev, Chambless, Lola B, Cooper, Michael K, Thompson, Reid C, Faria, Claudia C, Carvalho, Alice, Nunes, Sofia, Pimentel, José, Fan, Xing, Muraszko, Karin M, López-Aguilar, Enrique, Lyden, David, Garzia, Livia, Shih, David JH, Kijima, Noriyuki, Schneider, Christian, Adamski, Jennifer, Northcott, Paul A, Kool, Marcel, Jones, David TW, Chan, Jennifer A, Nikolic, Ana, Garre, Maria Luisa, Van Meir, Erwin G, Osuka, Satoru, Olson, Jeffrey J, Jahangiri, Arman, Castro, Brandyn A., Gupta, Nalin, Weiss, William A, Moxon-Emre, Iska, Mabbott, Donald J, Lassaletta, Alvaro, Hawkins, Cynthia E, Tabori, Uri, Drake, James, Kulkarni, Abhaya, Dirks, Peter, Rutka, James T, Korshunov, Andrey, Pfister, Stefan M, Packer, Roger J, Ramaswamy, Vijay, Taylor, Michael D
Published 2016