The chemical chaperone, PBA, reduces ER stress and autophagy and increases collagen IV a5 expression in cultured fibroblasts from men With X-linked alport syndrome and missense mut...

by Wang, Dongmao, Mohammad, Mardhiah, Wang, Yanyan, Tan, Rachel, Murray, Lydia S., Ricardo, Sharon, Dagher, Hayat, Agtmael, Tom van, Savige, Judy
Published 2017

Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke

by Murray, Lydia S., Lu, Yinhui, Taggart, Aislynn, Van Regemorter, Nicole, Vilain, Catheline, Abramowicz, Marc, Kadler, Karl E., Van Agtmael, Tom
Published 2014

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

by Jones, Frances E., Bailey, Matthew A., Murray, Lydia S., Lu, Yinhui, McNeilly, Sarah, Schlötzer-Schrehardt, Ursula, Lennon, Rachel, Sado, Yoshikazu, Brownstein, David G., Mullins, John J., Kadler, Karl E., Van Agtmael, Tom
Published 2016

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

by Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuív, Páraic Ó., McGuckin, Michael A., Hasnain, Sumaira Z.
Published 2016