Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice

by Dupouy, Sandra, Doan, Van Kien, Wu, Zherui, Mourra, Najat, Liu, Jin, De Wever, Olivier, Llorca, Frédérique Penault, Cayre, Anne, Kouchkar, Amal, Gompel, Anne, Forgez, Patricia
Published 2014

Neurotensin (NTS) and its receptor (NTSR1) causes EGFR, HER2 and HER3 over-expression and their autocrine/paracrine activation in lung tumors, confirming responsiveness to erlotini...

by Younes, Mohamad, Wu, Zherui, Dupouy, Sandra, Lupo, Audrey Mansuet, Mourra, Najat, Takahashi, Takashi, Fléjou, Jean François, Trédaniel, Jean, Régnard, Jean François, Damotte, Diane, Alifano, Marco, Forgez, Patricia
Published 2014