Dissecting the oligonucleotide binding properties of a disordered chaperone protein using surface plasmon resonance

by Baltzinger, Mireille, Sharma, Kamal Kant, Mély, Yves, Altschuh, Danièle
Published 2013

Site-selective probing of cTAR destabilization highlights the necessary plasticity of the HIV-1 nucleocapsid protein to chaperone the first strand transfer

by Godet, Julien, Kenfack, Cyril, Przybilla, Frédéric, Richert, Ludovic, Duportail, Guy, Mély, Yves
Published 2013

FRET-based assay to screen inhibitors of HIV-1 reverse transcriptase and nucleocapsid protein

by Sharma, Kamal K., Przybilla, Frédéric, Restle, Tobias, Godet, Julien, Mély, Yves
Published 2016

Bright and photostable push-pull pyrene dye visualizes lipid order variation between plasma and intracellular membranes

by Niko, Yosuke, Didier, Pascal, Mely, Yves, Konishi, Gen-ichi, Klymchenko, Andrey S.
Published 2016

Specific implications of the HIV-1 nucleocapsid zinc fingers in the annealing of the primer binding site complementary sequences during the obligatory plus strand transfer

by Godet, Julien, Ramalanjaona, Nick, Sharma, Kamal K., Richert, Ludovic, de Rocquigny, Hugues, Darlix, Jean-Luc, Duportail, Guy, Mély, Yves
Published 2011

8-vinyl-deoxyadenosine, an alternative fluorescent nucleoside analog to 2′-deoxyribosyl-2-aminopurine with improved properties

by Gaied, Nouha Ben, Glasser, Nicole, Ramalanjaona, Nick, Beltz, Hervé, Wolff, Philippe, Marquet, Roland, Burger, Alain, Mély, Yves
Published 2005

Intrinsic Nucleic Acid Dynamics Modulates HIV-1 Nucleocapsid Protein Binding to Its Targets

by Bazzi, Ali, Zargarian, Loussiné, Chaminade, Françoise, De Rocquigny, Hugues, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Published 2012

Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC

by Bazzi, Ali, Zargarian, Loussiné, Chaminade, Françoise, Boudier, Christian, De Rocquigny, Hughes, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Published 2011

Structural determinants of TAR RNA-DNA annealing in the absence and presence of HIV-1 nucleocapsid protein

by Kanevsky, Igor, Chaminade, Françoise, Chen, Yingying, Godet, Julien, René, Brigitte, Darlix, Jean-Luc, Mély, Yves, Mauffret, Olivier, Fossé, Philippe
Published 2011

Analysis of nucleic acid chaperoning by the prion protein and its inhibition by oligonucleotides

by Guichard, Cécile, Ivanyi-Nagy, Roland, Sharma, Kamal Kant, Gabus, Caroline, Marc, Daniel, Mély, Yves, Darlix, Jean-Luc
Published 2011

Analysis of the RNA chaperoning activity of the hepatitis C virus core protein on the conserved 3′X region of the viral genome

by Sharma, Kamal Kant, de Rocquigny, Hugues, Darlix, Jean Luc, Lavergne, Jean-Pierre, Pénin, François, Lessinger, Jean-Marc, Mély, Yves
Published 2012

Dynamic interactions of the HIV-1 Tat with nucleic acids are critical for Tat activity in reverse transcription

by Boudier, Christian, Humbert, Nicolas, Chaminade, Françoise, Chen, Yingying, de Rocquigny, Hugues, Godet, Julien, Mauffret, Olivier, Fossé, Philippe, Mély, Yves
Published 2014

Integrity of lipid nanocarriers in bloodstream and tumor quantified by near-infrared ratiometric FRET imaging in living mice

by Bouchaala, Redouane, Mercier, Luc, Andreiuk, Bohdan, Mély, Yves, Vandamme, Thierry, Anton, Nicolas, Goetz, Jacky G., Klymchenko, Andrey S.
Published 2016

Dynamics of Linker Residues Modulate the Nucleic Acid Binding Properties of the HIV-1 Nucleocapsid Protein Zinc Fingers

by Zargarian, Loussiné, Tisné, Carine, Barraud, Pierre, Xu, Xiaoqian, Morellet, Nelly, René, Brigitte, Mély, Yves, Fossé, Philippe, Mauffret, Olivier
Published 2014

Identification of a methylated oligoribonucleotide as a potent inhibitor of HIV-1 reverse transcription complex

by Grigorov, Boyan, Bocquin, Anne, Gabus, Caroline, Avilov, Sergey, Mély, Yves, Agopian, Audrey, Divita, Gilles, Gottikh, Marina, Witvrouw, Myriam, Darlix, Jean-Luc
Published 2011

Optimization and antiviral analysis of peptide ligands for the HIV-1 packaging signal PSI

by Dietz, Julia, Pustowka, Anette, Kaur, Ajit, Koch, Joachim, Mensch, Sarah, Stein, Stefan, Grez, Manuel, Divita, Gilles, Mély, Yves, Schwalbe, Harald, Dietrich, Ursula
Published 2006

Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16INK4A re-expression related to UHRF1 and DNMT1 down-regulation

by Krifa, Mounira, Alhosin, Mahmoud, Muller, Christian D, Gies, Jean-Pierre, Chekir-Ghedira, Leila, Ghedira, Kamel, Mély, Yves, Bronner, Christian, Mousli, Marc
Published 2013

Structural and functional studies of the HIV-1 pre-integration complex

by Levy, Nicolas, Eiler, Sylvia, Pradeau-Aubreton, Karine, Crucifix, Corinne, Schaetzel, Aurélie, Drillien, Robert, Parissi, Vincent, Emiliani, Stéphane, Mely, Yves, Schultz, Patrick, Ruff, Marc
Published 2013

A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

by Vercruysse, Thomas, Basta, Beata, Dehaen, Wim, Humbert, Nicolas, Balzarini, Jan, Debaene, François, Sanglier-Cianférani, Sarah, Pannecouque, Christophe, Mély, Yves, Daelemans, Dirk
Published 2012

Quantitative sampling of conformational heterogeneity of a DNA hairpin using molecular dynamics simulations and ultrafast fluorescence spectroscopy

by Voltz, Karine, Léonard, Jérémie, Touceda, Patricia Tourón, Conyard, Jamie, Chaker, Ziyad, Dejaegere, Annick, Godet, Julien, Mély, Yves, Haacke, Stefan, Stote, Roland H.
Published 2016