Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy

by Pettinati, Ilaria, Brem, Jürgen, McDonough, Michael A., Schofield, Christopher J.
Published 2015

Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation

by Aik, WeiShen, Scotti, John S., Choi, Hwanho, Gong, Lingzhi, Demetriades, Marina, Schofield, Christopher J., McDonough, Michael A.
Published 2014

Use of ferrous iron by metallo-β-lactamases

by Cahill, Samuel T., Tarhonskaya, Hanna, Rydzik, Anna M., Flashman, Emily, McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Published 2016

Oxygenase-Catalyzed Desymmetrization of N,N-Dialkyl-piperidine-4-carboxylic Acids**

by Rydzik, Anna M, Leung, Ivanhoe K H, Kochan, Grazyna T, McDonough, Michael A, Claridge, Timothy D W, Schofield, Christopher J
Published 2014

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

by Brem, Jürgen, van Berkel, Sander S., Zollman, David, Lee, Sook Y., Gileadi, Opher, McHugh, Peter J., Walsh, Timothy R., McDonough, Michael A., Schofield, Christopher J.
Published 2015

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles

by Makena, Anne, Düzgün, Azer Ö., Brem, Jürgen, McDonough, Michael A., Rydzik, Anna M., Abboud, Martine I., Saral, Ayşegül, Çiçek, Ayşegül Ç., Sandalli, Cemal, Schofield, Christopher J.
Published 2016

Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases

by Horita, Shoichiro, Scotti, John S., Thinnes, Cyrille, Mottaghi-Taromsari, Yousef S., Thalhammer, Armin, Ge, Wei, Aik, WeiShen, Loenarz, Christoph, Schofield, Christopher J., McDonough, Michael A.
Published 2015

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

by Yang, Ming, Chowdhury, Rasheduzzaman, Ge, Wei, Hamed, Refaat B, McDonough, Michael A, Claridge, Timothy D W, Kessler, Benedikt M, Cockman, Matthew E, Ratcliffe, Peter J, Schofield, Christopher J
Published 2011

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

by Brem, Jürgen, Cain, Ricky, Cahill, Samuel, McDonough, Michael A., Clifton, Ian J., Jiménez-Castellanos, Juan-Carlos, Avison, Matthew B., Spencer, James, Fishwick, Colin W. G., Schofield, Christopher J.
Published 2016

Cation–π Interactions Contribute to Substrate Recognition in γ‐Butyrobetaine Hydroxylase Catalysis

by Kamps, Jos J. A. G., Khan, Amjad, Choi, Hwanho, Lesniak, Robert K., Brem, Jürgen, Rydzik, Anna M., McDonough, Michael A., Schofield, Christopher J., Claridge, Timothy D. W., Mecinović, Jasmin
Published 2015

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1† †Electronic supplementary information (ESI) available: Procedures for protein expression and purifica...

by Brem, Jürgen, Struwe, Weston B., Rydzik, Anna M., Tarhonskaya, Hanna, Pfeffer, Inga, Flashman, Emily, van Berkel, Sander S., Spencer, James, Claridge, Timothy D. W., McDonough, Michael A., Benesch, Justin L. P., Schofield, Christopher J.
Published 2015

Pharmacological Inhibition of FTO

by McMurray, Fiona, Demetriades, Marina, Aik, WeiShen, Merkestein, Myrte, Kramer, Holger, Andrew, Daniel S., Scudamore, Cheryl L., Hough, Tertius A., Wells, Sara, Ashcroft, Frances M., McDonough, Michael A., Schofield, Christopher J., Cox, Roger D.
Published 2015

Ribosomal Oxygenases are Structurally Conserved from Prokaryotes to Humans

by Chowdhury, Rasheduzzaman, Sekirnik, Rok, Brissett, Nigel C., Krojer, Tobias, Ho, Chia-hua, Ng, Stanley S., Clifton, Ian J., Ge, Wei, Kershaw, Nadia J., Fox, Gavin C., Muniz, Joao R. C., Vollmar, Melanie, Phillips, Claire, Pilka, Ewa S., Kavanagh, Kathryn L., von Delft, Frank, Oppermann, Udo, McDonough, Michael A., Doherty, Aiden J., Schofield, Christopher J.
Published 2014