Recent progress in targeting cancer

by Demidenko, Zoya N., McCubrey, James A.
Published 2011

Recent discoveries in the cycling, growing and aging of the p53 field

by McCubrey, James A., Demidenko, Zoya N.
Published 2012

Exploiting p53 Status to Enhance Effectiveness of Chemotherapy by Lowering Associated Toxicity

by Steelman, Linda S., Martelli, Alberto M., Nicoletti, Ferdinando, McCubrey, James A.
Published 2011

Targeted therapy for hepatocellular carcinoma: novel agents on the horizon

by Cervello, Melchiorre, McCubrey, James A., Cusimano, Antonella, Lampiasi, Nadia, Azzolina, Antonina, Montalto, Giuseppe
Published 2012

Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells

by Cervello, Melchiorre, Bachvarov, Dimcho, Lampiasi, Nadia, Cusimano, Antonella, Azzolina, Antonina, McCubrey, James A., Montalto, Giuseppe
Published 2013

Enhancing the effectiveness of nucleoside analogs with mTORC1 blockers to treat acute myeloid leukemia patients

by Martelli, Alberto M., Lonetti, Annalisa, Amadori, Sergio, McCubrey, James A., Chiarini, Francesca
Published 2013

The Emerging Role of the Phosphatidylinositol 3-Kinase/ Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cell Biology

by Martelli, Alberto M., Evangelisti, Camilla, Chiarini, Francesca, Grimaldi, Cecilia, McCubrey, James A.
Published 2010

MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma

by Falzone, Luca, Salemi, Rossella, Travali, Salvatore, Scalisi, Aurora, McCubrey, James A., Candido, Saverio, Libra, Massimo
Published 2016

PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer

by Knostman, Katherine AB, McCubrey, James A, Morrison, Carl D, Zhang, Zhaoxia, Capen, Charles C, Jhiang, Sissy M
Published 2007

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment

by Martelli, Alberto M., Chiarini, Francesca, Evangelisti, Camilla, Cappellini, Alessandra, Buontempo, Francesca, Bressanin, Daniela, Fini, Milena, McCubrey, James A.
Published 2012

Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes

by Berman, Albert E., Leontieva, Olga V., Natarajan, Venkatesh, McCubrey, James A., Demidenko, Zoya N., Nikiforov, Mikhail A.
Published 2012

The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy

by Simioni, Carolina, Martelli, Alberto M., Cani, Alice, Cetin-Atalay, Rengul, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Published 2013

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer

by Candido, Saverio, Maestro, Roberta, Polesel, Jerry, Catania, Alessia, Maira, Francesca, Signorelli, Santo S., McCubrey, James A., Libra, Massimo
Published 2014

Computational Modeling of PI3K/AKT and MAPK Signaling Pathways in Melanoma Cancer

by Pappalardo, Francesco, Russo, Giulia, Candido, Saverio, Pennisi, Marzio, Cavalieri, Salvatore, Motta, Santo, McCubrey, James A., Nicoletti, Ferdinando, Libra, Massimo
Published 2016

A novel DAG-dependent mechanism links PKCa and Cyclin B1 regulating cell cycle progression

by Poli, Alessandro, Ramazzotti, Giulia, Matteucci, Alessandro, Manzoli, Lucia, Lonetti, Annalisa, Suh, Pann-Ghill, McCubrey, James A., Cocco, Lucio
Published 2014

Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells

by Cusimano, Antonella, Puleio, Roberto, D'Alessandro, Natale, Loria, Guido R., McCubrey, James A., Montalto, Giuseppe, Cervello, Melchiorre
Published 2014

PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells

by Bavelloni, Alberto, Poli, Alessandro, Fiume, Roberta, Blalock, William, Matteucci, Alessandro, Ramazzotti, Giulia, McCubrey, James A., Cocco, Lucio, Faenza, Irene
Published 2014

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels

by Bressanin, Daniela, Evangelisti, Camilla, Ricci, Francesca, Tabellini, Giovanna, Chiarini, Francesca, Tazzari, Pier Luigi, Melchionda, Fraia, Buontempo, Francesca, Pagliaro, Pasqualepaolo, Pession, Andrea, McCubrey, James A., Martelli, Alberto M.
Published 2012

Analysis of the B-RAFV600E mutation in cutaneous melanoma patients with occupational sun exposure

by CANDIDO, SAVERIO, RAPISARDA, VENERANDO, MARCONI, ANDREA, MALAPONTE, GRAZIA, BEVELACQUA, VALENTINA, GANGEMI, PIETRO, SCALISI, AURORA, McCUBREY, JAMES A., MAESTRO, ROBERTA, SPANDIDOS, DEMETRIOS A., FENGA, CONCETTINA, LIBRA, MASSIMO
Published 2014

Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia

by Cani, Alice, Simioni, Carolina, Martelli, Alberto M., Zauli, Giorgio, Tabellini, Giovanna, Ultimo, Simona, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Published 2015