Is there a role of synovial biopsy in drug development?

by Filkova, Maria, Cope, Andrew, Mant, Tim, Galloway, James
Published 2016

Maximum Tolerated Dose Evaluation of the AMPA Modulator Org 26576 in Healthy Volunteers and Depressed Patients: A Summary and Method Analysis of Bridging Research in Support of Pha...

by Nations, Kari R., Bursi, Roberta, Dogterom, Peter, Ereshefsky, Larry, Gertsik, Lev, Mant, Tim, Schipper, Jacques
Published 2012

Comparison of the pharmacokinetics, safety, and immunogenicity of MSB11022, a biosimilar of adalimumab, with Humira® in healthy subjects

by Hyland, Elizabeth, Mant, Tim, Vlachos, Pantelis, Attkins, Neil, Ullmann, Martin, Roy, Sanjeev, Wagner, Volker
Published 2016

Pharmacokinetics and Tolerability of the Novel Oral Prostacyclin IP Receptor Agonist Selexipag

by Kaufmann, Priska, Okubo, Kaori, Bruderer, Shirin, Mant, Tim, Yamada, Tetsuhiro, Dingemanse, Jasper, Mukai, Hideya
Published 2015

Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteo...

by Gow, Jason M., Tsuji, Wayne H., Williams, Gary J., Mytych, Daniel, Sciberras, David, Searle, Shawn L., Mant, Tim, Gibbs, John P.
Published 2015

Effects of CYP3A4 Inhibitors Ketoconazole and Verapamil and the CYP3A4 Inducer Rifampicin on the Pharmacokinetic Parameters of Fostamatinib: Results from In Vitro and Phase I Clini...

by Martin, Paul, Gillen, Michael, Millson, David, Oliver, Stuart, Brealey, Clive, Grossbard, Elliott B., Baluom, Muhammad, Lau, David, Sweeny, David, Mant, Tim, Craven, Kelli
Published 2016