Epigenetics in liver disease

by Mann, Derek A
Published 2014

Serotonin paracrine signaling in tissue fibrosis☆☆☆

by Mann, Derek A., Oakley, Fiona
Published 2013

Epigenetics in liver disease: from biology to therapeutics

by Hardy, Timothy, Mann, Derek A
Published 2016

Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells

by Corbett, Laura, Mann, Jelena, Mann, Derek A.
Published 2015

The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

by Elsharkawy, Ahmed M., Oakley, Fiona, Lin, Feng, Packham, Graham, Mann, Derek A., Mann, Jelena
Published 2010

Seamless replacement of Autographa californica multiple nucleopolyhedrovirus gp64 with each of five novel type II alphabaculovirus fusion sequences generates pseudotyped virus that...

by Westenberg, Marcel, Soedling, Helen M., Hirani, Nisha, Nicholson, Linda J., Mann, Derek A., Dolphin, Colin T.
Published 2012

An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury

by Robinson, Stuart M, Mann, Jelena, Manas, Derek M, Mann, Derek A, White, Steven A
Published 2013

Joint Stiffness Is Heritable and Associated with Fibrotic Conditions and Joint Replacement

by Williams, Frances M., Kalson, Nicholas S., Fabiane, Stella M., Mann, Derek A., Deehan, David J.
Published 2015

How Reliable Are Sino-Nasal Cell Lines for Studying the Pathophysiology of Chronic Rhinosinusitis?

by Ball, Stephen L., Suwara, Monika I., Borthwick, Lee A., Wilson, Janet A., Mann, Derek A., Fisher, Andrew J.
Published 2015

Fibrosis is a common outcome following total knee arthroplasty

by Abdul, Nicole, Dixon, David, Walker, Andrew, Horabin, Joanna, Smith, Nick, Weir, David J., Brewster, Nigel T., Deehan, David J., Mann, Derek A., Borthwick, Lee A.
Published 2015

Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation

by Perugorria, Maria Jesus, Wilson, Caroline L, Zeybel, Mujdat, Walsh, Meagan, Amin, Shilu, Robinson, Stuart, White, Steven A, Burt, Alastair D, Oakley, Fiona, Tsukamoto, Hidekazu, Mann, Derek A, Mann, Jelena
Published 2012

Multigenerational Epigenetic Adaptation of the Hepatic Wound-Healing Response

by Zeybel, Müjdat, Hardy, Timothy, Wong, Yi K., Mathers, John C., Fox, Christopher R., Gackowska, Agata, Oakley, Fiona, Burt, Alastair D., Wilson, Caroline L., Anstee, Quentin M., Barter, Matt J., Masson, Steven, Elsharkawy, Ahmed M., Mann, Derek A., Mann, Jelena
Published 2012

Osteopontin Is a Novel Downstream Target of SOX9 With Diagnostic Implications for Progression of Liver Fibrosis in Humans

by Pritchett, James, Harvey, Emma, Athwal, Varinder, Berry, Andrew, Rowe, Cliff, Oakley, Fiona, Moles, Anna, Mann, Derek A, Bobola, Nicoletta, Sharrocks, Andrew D, Thomson, Brian J, Zaitoun, Abed M, Irving, William L, Guha, Indra N, Hanley, Neil A, Hanley, Karen Piper
Published 2012

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse

by Moles, Anna, Murphy, Lindsay, Wilson, Caroline L., Chakraborty, Jayashree Bagchi, Fox, Christopher, Park, Eek Joong, Mann, Jelena, Oakley, Fiona, Howarth, Rachel, Brain, John, Masson, Steven, Karin, Michael, Seki, Ekihiro, Mann, Derek A.
Published 2014

Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3

by Wilson, Caroline L., Mann, Jelena, Walsh, Meagan, Perrugoria, Maria J., Oakley, Fiona, Wright, Matthew C., Brignole, Chiara, Di Paolo, Daniela, Perri, Patrizia, Ponzoni, Mirco, Karin, Michael, Mann, Derek A.
Published 2014

Inhibition of RelA-Ser536 Phosphorylation by a Competing Peptide Reduces Mouse Liver Fibrosis Without Blocking the Innate Immune Response

by Moles, Anna, Sanchez, Ana M, Banks, Paul S, Murphy, Lindsay B, Luli, Saimir, Borthwick, Lee, Fisher, Andrew, O’Reilly, Steven, van Laar, Jacob M, White, Steven A, Perkins, Neil D, Burt, Alastair D, Mann, Derek A, Oakley, Fiona
Published 2013

Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease

by Hardy, Timothy, Zeybel, Mujdat, Day, Christopher P, Dipper, Christian, Masson, Steven, McPherson, Stuart, Henderson, Elsbeth, Tiniakos, Dina, White, Steve, French, Jeremy, Mann, Derek A, Anstee, Quentin M, Mann, Jelena
Published 2017

Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription

by Lanucara, Francesco, Lam, Connie, Mann, Jelena, Monie, Tom P., Colombo, Stefano A. P., Holman, Stephen W., Boyd, James, Dange, Manohar C., Mann, Derek A., White, Michael R. H., Eyers, Claire E.
Published 2016

A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo

by Luli, Saimir, Di Paolo, Daniela, Perri, Patrizia, Brignole, Chiara, Hill, Stephen J., Brown, Helen, Leslie, Jack, Marshall, H.L., Wright, Matthew C., Mann, Derek A., Ponzoni, Mirco, Oakley, Fiona
Published 2016

A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty

by Dixon, David, Coates, Jonathon, del Carpio Pons, Alicia, Horabin, Joanna, Walker, Andrew, Abdul, Nicole, Kalson, Nicholas S., Brewster, Nigel T., Weir, David J., Deehan, David J., Mann, Derek A., Borthwick, Lee A.
Published 2015