Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression

by May, Caitlin D, Sphyris, Nathalie, Evans, Kurt W, Werden, Steven J, Guo, Wenjun, Mani, Sendurai A
Published 2011

Investigating the Link between Molecular Subtypes of Glioblastoma, Epithelial-Mesenchymal Transition, and CD133 Cell Surface Protein

by Zarkoob, Hadi, Taube, Joseph H., Singh, Sheila K., Mani, Sendurai A., Kohandel, Mohammad
Published 2013

GD2 and GD3 synthase: novel drug targets for cancer therapy

by Sphyris, Nathalie, Sarkar, Tapasree Roy, Battula, Venkata L, Andreeff, Michael, Mani, Sendurai A
Published 2015

A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome

by Soundararajan, Rama, Paranjape, Anurag N., Barsan, Valentin, Chang, Jeffrey T., Mani, Sendurai A.
Published 2015

Coupling the modules of EMT and stemness: A tunable ‘stemness window’ model

by Jolly, Mohit Kumar, Jia, Dongya, Boareto, Marcelo, Mani, Sendurai A., Pienta, Kenneth J., Ben-Jacob, Eshel, Levine, Herbert
Published 2015

Mathematical modelling of phenotypic plasticity and conversion to a stem-cell state under hypoxia

by Dhawan, Andrew, Madani Tonekaboni, Seyed Ali, Taube, Joseph H., Hu, Stephen, Sphyris, Nathalie, Mani, Sendurai A., Kohandel, Mohammad
Published 2016

FOXC2 regulates the G2/M transition of stem cell-rich breast cancer cells and sensitizes them to PLK1 inhibition

by Pietilä, Mika, Vijay, Geraldine V., Soundararajan, Rama, Yu, Xian, Symmans, William F., Sphyris, Nathalie, Mani, Sendurai A.
Published 2016

Overexpression of Snail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cells

by Fan, Fan, Samuel, Shaija, Evans, Kurt W, Lu, Jia, Xia, Ling, Zhou, Yunfei, Sceusi, Eric, Tozzi, Federico, Ye, Xiang-Cang, Mani, Sendurai A, Ellis, Lee M
Published 2012

Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients

by Román-Pérez, Erick, Casbas-Hernández, Patricia, Pirone, Jason R, Rein, Jessica, Carey, Lisa A, Lubet, Ronald A, Mani, Sendurai A, Amos, Keith D, Troester, Melissa A
Published 2012

Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Chang...

by Krohn, Alexander, Ahrens, Theresa, Yalcin, Arzu, Plönes, Till, Wehrle, Julius, Taromi, Sanaz, Wollner, Stefan, Follo, Marie, Brabletz, Thomas, Mani, Sendurai A., Claus, Rainer, Hackanson, Björn, Burger, Meike
Published 2014

Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype

by Boareto, Marcelo, Jolly, Mohit Kumar, Goldman, Aaron, Pietilä, Mika, Mani, Sendurai A., Sengupta, Shiladitya, Ben-Jacob, Eshel, Levine, Herbert, Onuchic, Jose’ N.
Published 2016

Stability of the hybrid epithelial/mesenchymal phenotype

by Jolly, Mohit Kumar, Tripathi, Satyendra C., Jia, Dongya, Mooney, Steven M., Celiktas, Muge, Hanash, Samir M., Mani, Sendurai A., Pienta, Kenneth J., Ben-Jacob, Eshel, Levine, Herbert
Published 2016

EMT-induced metabolite signature identifies poor clinical outcome

by Bhowmik, Salil Kumar, Ramirez-Peña, Esmeralda, Arnold, James Michael, Putluri, Vasanta, Sphyris, Nathalie, Michailidis, George, Putluri, Nagireddy, Ambs, Stefan, Sreekumar, Arun, Mani, Sendurai A.
Published 2015

Loss of breast epithelial marker hCLCA2 promotes epithelial to mesenchymal transition and indicates higher risk of metastasis

by Walia, Vijay, Yu, Yang, Cao, Deshou, Sun, Miao, McLean, Janel R., Hollier, Brett G., Cheng, Jiming, Mani, Sendurai A., Rao, Krishna, Premkumar, Louis, Elble, Randolph
Published 2011

Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties

by Taube, Joseph H., Malouf, Gabriel G., Lu, Emily, Sphyris, Nathalie, Vijay, Vidya, Ramachandran, Priyanka P., Ueno, Katumasa R., Gaur, Sanchaika, Nicoloso, Milena S., Rossi, Simona, Herschkowitz, Jason I., Rosen, Jeffrey M., Issa, Jean-Pierre J., Calin, George A., Chang, Jeffrey T., Mani, Sendurai A.
Published 2013

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition

by Malouf, Gabriel G, Taube, Joseph H, Lu, Yue, Roysarkar, Tapasree, Panjarian, Shoghag, Estecio, Marcos RH, Jelinek, Jaroslav, Yamazaki, Jumpei, Raynal, Noel J-M, Long, Hai, Tahara, Tomomitsu, Tinnirello, Agata, Ramachandran, Priyanka, Zhang, Xiu-Ying, Liang, Shoudan, Mani, Sendurai A, Issa, Jean-Pierre J
Published 2013

Inflammation Mediated Metastasis: Immune Induced Epithelial-To-Mesenchymal Transition in Inflammatory Breast Cancer Cells

by Cohen, Evan N., Gao, Hui, Anfossi, Simone, Mego, Michal, Reddy, Neelima G., Debeb, Bisrat, Giordano, Antonio, Tin, Sanda, Wu, Qiong, Garza, Raul J., Cristofanilli, Massimo, Mani, Sendurai A., Croix, Denise A., Ueno, Naoto T., Woodward, Wendy A., Luthra, Raja, Krishnamurthy, Savitri, Reuben, James M.
Published 2015