New vasorelaxant indole alkaloids, villocarines A-D from Uncaria villosa.

by Matsuo, Hirotaka, Okamoto, Ryuichi, Zaima, Kazumasa, Hirasawa, Yusuke, Ismail, Intan Safinar, Lajis, Md. Nordin, Morita, Hiroshi
Published 2011

Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations

by Miyata, Hiroshi, Takada, Tappei, Toyoda, Yu, Matsuo, Hirotaka, Ichida, Kimiyoshi, Suzuki, Hiroshi
Published 2016

Corrigendum: Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals

by Furukawa, Junji, Inoue, Katsuhisa, Maeda, Junya, Yasujima, Tomoya, Ohta, Kinya, Kanai, Yoshikatsu, Takada, Tappei, Matsuo, Hirotaka, Yuasa, Hiroaki
Published 2016

Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals

by Furukawa, Junji, Inoue, Katsuhisa, Maeda, Junya, Yasujima, Tomoya, Ohta, Kinya, Kanai, Yoshikatsu, Takada, Tappei, Matsuo, Hirotaka, Yuasa, Hiroaki
Published 2015

ASSOCIATIONS BETWEEN BODY MASS INDEX AND SERUM URIC ACID LEVELS IN A JAPANESE POPULATION WERE SIGNIFICANTLY MODIFIED BY LRP2 rs2544390

by SUMA, SHINO, NAITO, MARIKO, OKADA, RIEKO, KAWAI, SAYO, YIN, GUANG, MORITA, EMI, WAKAI, KENJI, MATSUO, HIROTAKA, HAMAJIMA, NOBUYUKI
Published 2014

Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility

by Nakayama, Akiyoshi, Matsuo, Hirotaka, Shimizu, Toru, Takada, Yuzo, Nakamura, Takahiro, Shimizu, Seiko, Chiba, Toshinori, Sakiyama, Masayuki, Naito, Mariko, Morita, Emi, Ichida, Kimiyoshi, Shinomiya, Nariyoshi
Published 2013

Up-Regulation of Antioxidant Proteins in the Plasma Proteome during Saturation Diving: Unique Coincidence under Hypobaric Hypoxia

by Domoto, Hideharu, Iwaya, Keiichi, Ikomi, Fumitaka, Matsuo, Hirotaka, Tadano, Yutaka, Fujii, Shigenori, Tachi, Kazuyoshi, Itoh, Yoshiyuki, Sato, Michiya, Inoue, Kimitoshi, Shinomiya, Nariyoshi
Published 2016

Identification of rs671, a common variant of ALDH2, as a gout susceptibility locus

by Sakiyama, Masayuki, Matsuo, Hirotaka, Nakaoka, Hirofumi, Yamamoto, Ken, Nakayama, Akiyoshi, Nakamura, Takahiro, Kawai, Sayo, Okada, Rieko, Ooyama, Hiroshi, Shimizu, Toru, Shinomiya, Nariyoshi
Published 2016

Carrier frequency of the GJB2 mutations that cause hereditary hearing loss in the Japanese population

by Taniguchi, Mirei, Matsuo, Hirotaka, Shimizu, Seiko, Nakayama, Akiyoshi, Suzuki, Koji, Hamajima, Nobuyuki, Shinomiya, Nariyoshi, Nishio, Shinya, Kosugi, Shinji, Usami, Shin-ichi, Ito, Juichi, Kitajiri, Shin-ichiro
Published 2015

NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea

by Honkura, Yohei, Matsuo, Hirotaka, Murakami, Shohei, Sakiyama, Masayuki, Mizutari, Kunio, Shiotani, Akihiro, Yamamoto, Masayuki, Morita, Ichiro, Shinomiya, Nariyoshi, Kawase, Tetsuaki, Katori, Yukio, Motohashi, Hozumi
Published 2016

Common variant of ALPK1 is not associated with gout: a replication study

by Chiba, Toshinori, Matsuo, Hirotaka, Sakiyama, Masayuki, Nakayama, Akiyoshi, Shimizu, Seiko, Wakai, Kenji, Suma, Shino, Nakashima, Hiroshi, Sakurai, Yutaka, Shimizu, Toru, Ichida, Kimiyoshi, Shinomiya, Nariyoshi
Published 2014

NO ASSOCIATION BETWEEN MTHFR C677T AND SERUM URIC ACID LEVELS AMONG JAPANESE WITH ABCG2 126QQ AND SLC22A12 258WW

by HINOHARA, YUKAKO, NAITO, MARIKO, OKADA, RIEKO, YIN, GUAN, HIGASHIBATA, TAKAHIRO, TAMURA, TAKASHI, KAWAI, SAYO, MORITA, EMI, WAKAI, KENJI, MATSUO, HIROTAKA, MORI, ATSUYOSHI, HAMAJIMA, NOBUYUKI
Published 2013

High levels of DJ-1 protein and isoelectric point 6.3 isoform in sera of breast cancer patients

by Kawate, Takahiko, Iwaya, Keiichi, Koshikawa, Kayoko, Moriya, Tomoyuki, Yamasaki, Tamio, Hasegawa, Sho, Kaise, Hiroshi, Fujita, Tomoyuki, Matsuo, Hirotaka, Nakamura, Takahiro, Ishikawa, Takashi, Hiroi, Sadayuki, Iguchi-Ariga, Sanae MM, Ariga, Hiroyoshi, Murota, Keiichi, Fujimori, Minoru, Yamamoto, Junji, Matsubara, Osamu, Kohno, Norio
Published 2015

Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

by Matsuo, Hirotaka, Tsunoda, Tomoyuki, Ooyama, Keiko, Sakiyama, Masayuki, Sogo, Tsuyoshi, Takada, Tappei, Nakashima, Akio, Nakayama, Akiyoshi, Kawaguchi, Makoto, Higashino, Toshihide, Wakai, Kenji, Ooyama, Hiroshi, Hokari, Ryota, Suzuki, Hiroshi, Ichida, Kimiyoshi, Inui, Ayano, Fujimori, Shin, Shinomiya, Nariyoshi
Published 2016

The effects of URAT1/SLC22A12 nonfunctional variants,R90H and W258X, on serum uric acid levels and gout/hyperuricemia progression

by Sakiyama, Masayuki, Matsuo, Hirotaka, Shimizu, Seiko, Nakashima, Hiroshi, Nakamura, Takahiro, Nakayama, Akiyoshi, Higashino, Toshihide, Naito, Mariko, Suma, Shino, Hishida, Asahi, Satoh, Takahiro, Sakurai, Yutaka, Takada, Tappei, Ichida, Kimiyoshi, Ooyama, Hiroshi, Shimizu, Toru, Shinomiya, Nariyoshi
Published 2016

ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout

by Matsuo, Hirotaka, Tomiyama, Hiroyuki, Satake, Wataru, Chiba, Toshinori, Onoue, Hiroyuki, Kawamura, Yusuke, Nakayama, Akiyoshi, Shimizu, Seiko, Sakiyama, Masayuki, Funayama, Manabu, Nishioka, Kenya, Shimizu, Toru, Kaida, Kenichi, Kamakura, Keiko, Toda, Tatsushi, Hattori, Nobutaka, Shinomiya, Nariyoshi
Published 2015

Decreased extra-renal urate excretion is a common cause of hyperuricemia

by Ichida, Kimiyoshi, Matsuo, Hirotaka, Takada, Tappei, Nakayama, Akiyoshi, Murakami, Keizo, Shimizu, Toru, Yamanashi, Yoshihide, Kasuga, Hiroshi, Nakashima, Hiroshi, Nakamura, Takahiro, Takada, Yuzo, Kawamura, Yusuke, Inoue, Hiroki, Okada, Chisa, Utsumi, Yoshitaka, Ikebuchi, Yuki, Ito, Kousei, Nakamura, Makiko, Shinohara, Yoshihiko, Hosoyamada, Makoto, Sakurai, Yutaka, Shinomiya, Nariyoshi, Hosoya, Tatsuo, Suzuki, Hiroshi
Published 2012

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

by Matsuo, Hirotaka, Ichida, Kimiyoshi, Takada, Tappei, Nakayama, Akiyoshi, Nakashima, Hiroshi, Nakamura, Takahiro, Kawamura, Yusuke, Takada, Yuzo, Yamamoto, Ken, Inoue, Hiroki, Oikawa, Yuji, Naito, Mariko, Hishida, Asahi, Wakai, Kenji, Okada, Chisa, Shimizu, Seiko, Sakiyama, Masayuki, Chiba, Toshinori, Ogata, Hiraku, Niwa, Kazuki, Hosoyamada, Makoto, Mori, Atsuyoshi, Hamajima, Nobuyuki, Suzuki, Hiroshi, Kanai, Yoshikatsu, Sakurai, Yutaka, Hosoya, Tatsuo, Shimizu, Toru, Shinomiya, Nariyoshi
Published 2013

A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility

by Nakayama, Akiyoshi, Matsuo, Hirotaka, Shimizu, Takuya, Ogata, Hiraku, Takada, Yuzo, Nakashima, Hiroshi, Nakamura, Takahiro, Shimizu, Seiko, Chiba, Toshinori, Sakiyama, Masayuki, Ushiyama, Chisaki, Takada, Tappei, Inoue, Katsuhisa, Kawai, Sayo, Hishida, Asahi, Wakai, Kenji, Hamajima, Nobuyuki, Ichida, Kimiyoshi, Sakurai, Yutaka, Kato, Yukio, Shimizu, Toru, Shinomiya, Nariyoshi
Published 2013

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

by Matsuo, Hirotaka, Nakayama, Akiyoshi, Sakiyama, Masayuki, Chiba, Toshinori, Shimizu, Seiko, Kawamura, Yusuke, Nakashima, Hiroshi, Nakamura, Takahiro, Takada, Yuzo, Oikawa, Yuji, Takada, Tappei, Nakaoka, Hirofumi, Abe, Junko, Inoue, Hiroki, Wakai, Kenji, Kawai, Sayo, Guang, Yin, Nakagawa, Hiroko, Ito, Toshimitsu, Niwa, Kazuki, Yamamoto, Ken, Sakurai, Yutaka, Suzuki, Hiroshi, Hosoya, Tatsuo, Ichida, Kimiyoshi, Shimizu, Toru, Shinomiya, Nariyoshi
Published 2014