Therapeutic Potential of the Translation Inhibitor Silvestrol in Hepatocellular Cancer

by Kogure, Takayuki, Kinghorn, A. Douglas, Yan, Irene, Bolon, Brad, Lucas, David M., Grever, Michael R., Patel, Tushar
Published 2013

Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis

by Singh, Rajbir, Mortazavi, Amir, Telu, Kelly H., Nagarajan, Prabakaran, Lucas, David M., Thomas-Ahner, Jennifer M., Clinton, Steven K., Byrd, John C., Freitas, Michael A., Parthun, Mark R.
Published 2013

Proteomic profiling identifies specific histone species associated with leukemic and cancer cells

by Singh, Rajbir, Harshman, Sean W., Ruppert, Amy S., Mortazavi, Amir, Lucas, David M., Thomas-Ahner, Jennifer M., Clinton, Steven K., Byrd, John C., Freitas, Michael A., Parthun, Mark R.
Published 2015

A Phase I/II Study of Etanercept and Rituximab in Patients with Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

by Woyach, Jennifer A, Lin, Thomas S, Lucas, Margaret S, Heerema, Nyla, Moran, Mollie E., Cheney, Carolyn, Lucas, David M., Wei, Lai, Caligiuri, Michael A., Byrd, John C.
Published 2009

Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

by Alachkar, Houda, Santhanam, Ramasamy, Harb, Jason G, Lucas, David M, Oaks, Joshua J, Hickey, Christopher J, Pan, Li, Kinghorn, A Douglas, Caligiuri, Michael A, Perrotti, Danilo, Byrd, John C, Garzon, Ramiro, Grever, Michael R, Marcucci, Guido
Published 2013

Involvement of RhoH GTPase in the Development of B-Cell Chronic Lymphocytic Leukemia

by Sanchez-Aguilera, Abel, Rattmann, Ina, Drew, David Z., Müller, Lars U.W., Summey, Victoria, Lucas, David M., Byrd, John C., Croce, Carlo M., Gu, Yi, Cancelas, Jose A., Johnston, Patrick, Moritz, Thomas, Williams, David A.
Published 2009

The translation inhibitor silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease

by Patton, John T., Lustberg, Mark E., Lozanski, Gerard, Garman, Sabrina L., Towns, William H., Drohan, Callie M., Lehman, Amy, Zhang, Xiaoli, Bolon, Brad, Pan, Li, Kinghorn, A. Douglas, Grever, Michael R., Lucas, David M., Baiocchi, Robert A.
Published 2014

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia

by Chen, Timothy L., Gupta, Nikhil, Lehman, Amy, Ruppert, Amy S., Yu, Lianbo, Oakes, Christopher C., Claus, Rainer, Plass, Christoph, Maddocks, Kami J., Andritsos, Leslie, Jones, Jeffery A., Lucas, David M., Johnson, Amy J., Byrd, John C., Hertlein, Erin
Published 2016

Sorbicillinoid Analogues with Cytotoxic and Selective Anti-Aspergillus Activities from Scytalidium album

by El-Elimat, Tamam, Raja, Huzefa A., Figueroa, Mario, Swanson, Steven M., Falkinham, Joseph O., Lucas, David M., Grever, Michael R., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.
Published 2014

Next generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematologic malignancies

by Hing, Zachary A., Fung, Ho Yee Joyce, Ranganathan, Parvathi, Mitchell, Shaneice, El-Gamal, Dalia, Woyach, Jennifer A., Williams, Katie, Goettl, Virginia M., Smith, Jordan, Yu, Xueyan, Meng, Xiaomei, Sun, Qingxiang, Cagatay, Tolga, Lehman, Amy M., Lucas, David M., Baloglu, Erkan, Shacham, Sharon, Kauffman, Michael G., Byrd, John C., Chook, Yuh Min, Garzon, Ramiro, Lapalombella, Rosa
Published 2016

Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia

by Raval, Aparna, Tanner, Stephan M., Byrd, John C., Angerman, Elizabeth B., Perko, James D., Chen, Shih-Shih, Hackanson, Björn, Grever, Michael R., Lucas, David M., Matkovic, Jennifer J., Lin, Thomas S., Kipps, Thomas J., Murray, Fiona, Weisenburger, Dennis, Sanger, Warren, Lynch, Jane, Watson, Patrice, Jansen, Mary, Yoshinaga, Yuko, Rosenquist, Richard, de Jong, Pieter J., Coggill, Penny, Beck, Stephan, Lynch, Henry, de la Chapelle, Albert, Plass, Christoph
Published 2007