Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis

by Welin, Amanda, Eklund, Daniel, Stendahl, Olle, Lerm, Maria
Published 2011

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue

by Parasa, Venkata Ramanarao, Rahman, Muhammad Jubayer, Ngyuen Hoang, Anh Thu, Svensson, Mattias, Brighenti, Susanna, Lerm, Maria
Published 2014

Human Gene Variants Linked to Enhanced NLRP3 Activity Limit Intramacrophage Growth of Mycobacterium tuberculosis

by Eklund, Daniel, Welin, Amanda, Andersson, Henrik, Verma, Deepti, Söderkvist, Peter, Stendahl, Olle, Särndahl, Eva, Lerm, Maria
Published 2014

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

by Braian, Clara, Svensson, Mattias, Brighenti, Susanna, Lerm, Maria, Parasa, Venkata R.
Published 2015

The Q705K Polymorphism in NLRP3 Is a Gain-of-Function Alteration Leading to Excessive Interleukin-1β and IL-18 Production

by Verma, Deepti, Särndahl, Eva, Andersson, Henrik, Eriksson, Per, Fredrikson, Mats, Jönsson, Jan-Ingvar, Lerm, Maria, Söderkvist, Peter
Published 2012

Replication Rates of Mycobacterium tuberculosis in Human Macrophages Do Not Correlate with Mycobacterial Antibiotic Susceptibility

by Raffetseder, Johanna, Pienaar, Elsje, Blomgran, Robert, Eklund, Daniel, Patcha Brodin, Veronika, Andersson, Henrik, Welin, Amanda, Lerm, Maria
Published 2014

Apoptotic Neutrophils Augment the Inflammatory Response to Mycobacterium tuberculosis Infection in Human Macrophages

by Andersson, Henrik, Andersson, Blanka, Eklund, Daniel, Ngoh, Eyler, Persson, Alexander, Svensson, Kristoffer, Lerm, Maria, Blomgran, Robert, Stendahl, Olle
Published 2014

Common Genetic Variations in the NALP3 Inflammasome Are Associated with Delayed Apoptosis of Human Neutrophils

by Blomgran, Robert, Patcha Brodin, Veronika, Verma, Deepti, Bergström, Ida, Söderkvist, Peter, Sjöwall, Christopher, Eriksson, Per, Lerm, Maria, Stendahl, Olle, Särndahl, Eva
Published 2012

Resistance to First-Line Anti-TB Drugs Is Associated with Reduced Nitric Oxide Susceptibility in Mycobacterium tuberculosis

by Idh, Jonna, Mekonnen, Mekidim, Abate, Ebba, Wedajo, Wassihun, Werngren, Jim, Ängeby, Kristian, Lerm, Maria, Elias, Daniel, Sundqvist, Tommy, Aseffa, Abraham, Stendahl, Olle, Schön, Thomas
Published 2012

TRIM27 Negatively Regulates NOD2 by Ubiquitination and Proteasomal Degradation

by Zurek, Birte, Schoultz, Ida, Neerincx, Andreas, Napolitano, Luisa M., Birkner, Katharina, Bennek, Eveline, Sellge, Gernot, Lerm, Maria, Meroni, Germana, Söderholm, Johan D., Kufer, Thomas A.
Published 2012