Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis

by Lanoix, Jean-Philippe, Lenaerts, Anne J., Nuermberger, Eric L.
Published 2015

Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer

by Fávaro, Wagner J, Nunes, Odilon S, Seiva, Fabio RF, Nunes, Iseu S, Woolhiser, Lisa K, Durán, Nelson, Lenaerts, Anne J
Published 2012

In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics

by Bruhn, David F., Scherman, Michael S., Liu, Jiuyu, Scherbakov, Dimitri, Meibohm, Bernd, Böttger, Erik C., Lenaerts, Anne J., Lee, Richard E.
Published 2015

Location of Intra- and Extracellular M. tuberculosis Populations in Lungs of Mice and Guinea Pigs during Disease Progression and after Drug Treatment

by Hoff, Donald R., Ryan, Gavin J., Driver, Emily R., Ssemakulu, Cornelius C., De Groote, Mary A., Basaraba, Randall J., Lenaerts, Anne J.
Published 2011

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

by Irwin, Scott M., Driver, Emily, Lyon, Edward, Schrupp, Christopher, Ryan, Gavin, Gonzalez-Juarrero, Mercedes, Basaraba, Randall J., Nuermberger, Eric L., Lenaerts, Anne J.
Published 2015

Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis

by Rakesh, Bruhn, David F., Scherman, Michael S., Woolhiser, Lisa K., Madhura, Dora B., Maddox, Marcus M., Singh, Aman P., Lee, Robin B., Hurdle, Julian G., McNeil, Michael R., Lenaerts, Anne J., Meibohm, Bernd, Lee, Richard E.
Published 2014

INHIBITION OF MYCOLIC ACID TRANSPORT ACROSS THE MYCOBACTERIUM TUBERCULOSIS PLASMA MEMBRANE

by Grzegorzewicz, Anna E., Pham, Ha, Gundi, Vijay A. K. B., Scherman, Michael S., North, Elton J., Hess, Tamara, Jones, Victoria, Gruppo, Veronica, Born, Sarah E. M., Korduláková, Jana, Chavadi, Sivagami Sundaram, Morisseau, Christophe, Lenaerts, Anne J., Lee, Richard E., McNeil, Michael R., Jackson, Mary
Published 2012

Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice

by Irwin, Scott M., Prideaux, Brendan, Lyon, Edward R., Zimmerman, Matthew D., Brooks, Elizabeth J., Schrupp, Christopher A., Chen, Chao, Reichlen, Matthew J., Asay, Bryce C., Voskuil, Martin I., Nuermberger, Eric L., Andries, Koen, Lyons, Michael A., Dartois, Véronique, Lenaerts, Anne J.
Published 2016

Spectinamides: A New Class of Semisynthetic Anti-Tuberculosis Agents that Overcome Native Drug Efflux

by Lee, Richard E., Hurdle, Julian G., Liu, Jiuyu, Bruhn, David F., Matt, Tanja, Scherman, Michael S., Vaddady, Pavan K, Zheng, Zhong, Qi, Jianjun, Akbergenov, Rashid, Das, Sourav, Madhura, Dora B., Rathi, Chetan, Trivedi, Ashit, Villellas, Cristina, Lee, Robin. B., Rakesh, Waidyarachchi, Samanthi L., Sun, Dianqing, McNeil, Michael R., Ainsa, Jose A., Boshoff, Helena I., Gonzalez-Juarrero, Mercedes, Meibohm, Bernd, Böttger, Erik C., Lenaerts, Anne J.
Published 2014

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

by Palencia, Andrés, Li, Xianfeng, Bu, Wei, Choi, Wai, Ding, Charles Z., Easom, Eric E., Feng, Lisa, Hernandez, Vincent, Houston, Paul, Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Rock, Fernando L., Sexton, Holly, Zhang, Suoming, Zhou, Yasheen, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G., Woolhiser, Lisa, Gruppo, Veronica, Lenaerts, Anne J., O'Malley, Theresa, Parish, Tanya, Cooper, Christopher B., Waters, M. Gerard, Ma, Zhenkun, Ioerger, Thomas R., Sacchettini, James C., Rullas, Joaquín, Angulo-Barturen, Iñigo, Pérez-Herrán, Esther, Mendoza, Alfonso, Barros, David, Cusack, Stephen, Plattner, Jacob J., Alley, M. R. K.
Published 2016