Open Access Target Validation Is a More Efficient Way to Accelerate Drug Discovery

by Lee, Wen Hwa
Published 2015

Accelerating target discovery using pre-competitive open science—patients need faster innovation more than anyone else

by Low, Eric, Bountra, Chas, Lee, Wen Hwa
Published 2016

Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint

by Wei, Randy, Ngo, Bryan, Wu, Guikai, Lee, Wen-Hwa
Published 2011

Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes

by Kao, Shih-Han, Wu, Kou-Juey, Lee, Wen-Hwa
Published 2016

Targeting interleukin-17 receptors

by Lee, Wen-Hwa, Wu, Heng-Hsiung, Huang, Chun-Kai
Published 2015

Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif*

by Llanos, Susana, Royer, Christophe, Lu, Min, Bergamaschi, Daniele, Lee, Wen Hwa, Lu, Xin
Published 2011

Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress

by Wei, Pei-Chi, Lo, Wen-Ting, Su, Mei-I., Shew, Jin-Yuh, Lee, Wen-Hwa
Published 2012

Biomarkers to Target Heterogeneous Breast Cancer Stem Cells

by Hwang-Verslues, Wendy W., Lee, Wen-Hwa, Lee, Eva Y.-H.P.
Published 2012

Structural basis of fumarate hydratase deficiency

by Picaud, Sarah, Kavanagh, Kathryn L., Yue, Wyatt W., Lee, Wen Hwa, Muller-Knapp, Susanne, Gileadi, Opher, Sacchettini, James, Oppermann, Udo
Published 2011

A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency

by Shafqat, Naeem, Kavanagh, Kate L., Sass, Jörn Oliver, Christensen, Ernst, Fukao, Toshiyuki, Lee, Wen Hwa, Oppermann, Udo, Yue, Wyatt W.
Published 2013

NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress

by Chen, Po-Jen, Weng, Jui-Yun, Hsu, Pang-Hung, Shew, Jin-Yuh, Huang, Yi-Shuian, Lee, Wen-Hwa
Published 2015

Characterization of 14-3-3 Proteins from Cryptosporidium parvum

by Brokx, Stephen J., Wernimont, Amy K., Dong, Aiping, Wasney, Gregory A., Lin, Yu-Hui, Lew, Jocelyne, Vedadi, Masoud, Lee, Wen Hwa, Hui, Raymond
Published 2011

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs

by Eswaran, Jeyanthy, Lee, Wen Hwa, Debreczeni, Judit É., Filippakopoulos, Panagis, Turnbull, Andrew, Fedorov, Oleg, Deacon, Sean W., Peterson, Jeffrey R., Knapp, Stefan
Published 2007

Comparative Structural Analysis of Lipid Binding START Domains

by Thorsell, Ann-Gerd, Lee, Wen Hwa, Persson, Camilla, Siponen, Marina I., Nilsson, Martina, Busam, Robert D., Kotenyova, Tetyana, Schüler, Herwig, Lehtiö, Lari
Published 2011

Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan

by Chen, Phang-Lang, Chen, Chi-Fen, Chen, Yumay, Guo, Xuning Emily, Huang, Chun-Kai, Shew, Jin-Yuh, Reddick, Robert L., Wallace, Douglas C., Lee, Wen-Hwa
Published 2012

Loss of ZBRK1 Contributes to the Increase of KAP1 and Promotes KAP1-Mediated Metastasis and Invasion in Cervical Cancer

by Lin, Li-Fang, Li, Chien-Feng, Wang, Wei-Jan, Yang, Wen-Ming, Wang, Dennis Ding-Hwa, Chang, Wen-Chang, Lee, Wen-Hwa, Wang, Ju-Ming
Published 2013

A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress

by Wei, Pei-Chi, Wang, Zi-Fu, Lo, Wen-Ting, Su, Mei-I, Shew, Jin-Yuh, Chang, Ta-Chau, Lee, Wen-Hwa
Published 2013

Erratum: Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

by Yin, Shu-Yi, Jian, Feng-Yin, Chen, Yung-Hsiang, Chien, Shih-Chang, Hsieh, Mao-Chih, Hsiao, Pei-Wen, Lee, Wen-Hwa, Kuo, Yueh-Hsiung, Yang, Ning-Sun
Published 2016

Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3

by Lee, Wen Hwa, Schaffner-Reckinger, Elisabeth, Tsoukatos, Demokritos C., Aylward, Kelly, Moussis, Vassilios, Tsikaris, Vassilios, Trypou, Paraskevi, Egot, Marion, Baruch, Dominique, Kieffer, Nelly, Bachelot-Loza, Christilla
Published 2015

Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

by Yin, Shu-Yi, Jian, Feng-Yin, Chen, Yung-Hsiang, Chien, Shih-Chang, Hsieh, Mao-Chih, Hsiao, Pei-Wen, Lee, Wen-Hwa, Kuo, Yueh-Hsiung, Yang, Ning-Sun
Published 2016