Identification of novel peroxisome proliferator-activated receptor-gamma (PPAR[gamma]) agonists using molecular modeling method

by Kumar, Alan Prem
Published 2014

Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases

by Zhu, Y., Casey, P., Kumar, Alan Prem, Pervaiz, S.
Published 2013

Targeting PPARy signaling cascade for the prevention and treatment of prostate cancer

by Sikka, S., Chen, L., Sethi, G., Kumar, Alan Prem
Published 2012

Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells

by Warrier, S., Balu, S., Kumar, Alan Prem, Michael, M., Dharmarajan, Arunasalam
Published 2014

Targeting PPARγ Signaling Cascade for the Prevention and Treatment of Prostate Cancer

by Sikka, Sakshi, Chen, Luxi, Sethi, Gautam, Kumar, Alan Prem
Published 2012

RNA helicase DP103 and TAK1: a new connection in cancer

by Shin, Eun Myoung, Osato, Motomi, Kumar, Alan Prem, Tergaonkar, Vinay
Published 2015

Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma

by Li, F., Shanmugam, M., Chen, L., Chatterjee, S., Basha, J., Kumar, Alan Prem, Kundu, T., Sethi, G.
Published 2013

Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies

by Shanmugam, M., Dai, X., Kumar, Alan Prem, Tan, B., Sethi, G., Bishayee, A.
Published 2013

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

by Shrimali, D., Shanmugam, M., Kumar, Alan Prem, Zhang, J., Tan, B., Ahn, K., Sethi, G.
Published 2013

Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: The role of p38 MAPK and ROS

by Woo, C., Hsu, A., Kumar, Alan Prem, Sethi, G., Tan, K.
Published 2013

Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma

by Sikka, S., Shanmugam, M., Kannaiyan, R., Surana, R., Shin, E., Kumar, Alan Prem, Sethi, G., Ahn, K.
Published 2014

Effects of Migrating Cell-Induced Matrix Reorganization on 3D Cancer Cell Migration

by Sun, W., Kurniawan, N., Kumar, Alan Prem, Rajagopalan, R., Lim, C.
Published 2014

Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS

by Woo, Chern Chiuh, Hsu, Annie, Kumar, Alan Prem, Sethi, Gautam, Tan, Kwong Huat Benny
Published 2013

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

by Singh, S., Yap, W., Arfuso, Frank, Kar, S., Wang, C., Cai, W., Dharmarajan, Arunasalam, Sethi, Gautam, Kumar, Alan Prem
Published 2015

NF-κB in cancer therapy

by Li, F., Zhang, J., Arfuso, Frank, Chinnathambi, A., Zayed, M., Alharbi, S., Kumar, Alan Prem, Ahn, K., Sethi, G.
Published 2015

Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors

by Siveen, K., Sikka, S., Surana, R., Dai, X., Zhang, J., Kumar, Alan Prem, Tan, B., Sethi, G., Bishayee, A.
Published 2013

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse mod...

by Siveen, K., Mustafa, N., Li, F., Kannaiyan, R., Ahn, K., Kumar, Alan Prem, Chng, W., Sethi, G.
Published 2014

Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model

by Shanmugam, M., Rajendran, P., Li, F., Kim, C., Sikka, S., Siveen, K., Kumar, Alan Prem, Ahn, K., Sethi, G.
Published 2015

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products

by Manu, K., Shanmugam, M., Li, F., Chen, L., Siveen, K., Ahn, K., Kumar, Alan Prem, Sethi, G.
Published 2013

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer

by Prasannan, R., Kalesh, K., Shanmugam, M., Nachiyappan, A., Ramachandran, L., Nguyen, A., Kumar, Alan Prem, Lakshmanan, M., Ahn, K., Gautam, S.
Published 2012