Deciphering the pathogenic consequences of chromosomal aberrations in human genetic disease

by Kloosterman, Wigard P, Hochstenbach, Ron
Published 2014

Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

by Kloosterman, Wigard P, Lagendijk, Anne K, Ketting, René F, Moulton, Jon D, Plasterk, Ronald H. A
Published 2007

Substrate requirements for let-7 function in the developing zebrafish embryo

by Kloosterman, Wigard P., Wienholds, Erno, Ketting, René F., Plasterk, Ronald H.A.
Published 2016

The presence of extra chromosomes leads to genomic instability

by Passerini, Verena, Ozeri-Galai, Efrat, de Pagter, Mirjam S., Donnelly, Neysan, Schmalbrock, Sarah, Kloosterman, Wigard P., Kerem, Batsheva, Storchová, Zuzana
Published 2016

Cloning and expression of new microRNAs from zebrafish

by Kloosterman, Wigard P., Steiner, Florian A., Berezikov, Eugene, de Bruijn, Ewart, van de Belt, Jose, Verheul, Mark, Cuppen, Edwin, Plasterk, Ronald H.A.
Published 2006

ViVar: A Comprehensive Platform for the Analysis and Visualization of Structural Genomic Variation

by Sante, Tom, Vergult, Sarah, Volders, Pieter-Jan, Kloosterman, Wigard P., Trooskens, Geert, De Preter, Katleen, Dheedene, Annelies, Speleman, Frank, De Meyer, Tim, Menten, Björn
Published 2014

Mouse microRNA profiles determined with a new and sensitive cloning method

by Takada, Shuji, Berezikov, Eugene, Yamashita, Yoshihiro, Lagos-Quintana, Mariana, Kloosterman, Wigard P., Enomoto, Munehiro, Hatanaka, Hisashi, Fujiwara, Shin-ichiro, Watanabe, Hideki, Soda, Manabu, Choi, Young Lim, Plasterk, Ronald H. A., Cuppen, Edwin, Mano, Hiroyuki
Published 2006

Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing

by van Heesch, Sebastiaan, Kloosterman, Wigard P, Lansu, Nico, Ruzius, Frans-Paul, Levandowsky, Elizabeth, Lee, Clarence C, Zhou, Shiguo, Goldstein, Steve, Schwartz, David C, Harkins, Timothy T, Guryev, Victor, Cuppen, Edwin
Published 2013

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

by Kloosterman, Wigard P, Hoogstraat, Marlous, Paling, Oscar, Tavakoli-Yaraki, Masoumeh, Renkens, Ivo, Vermaat, Joost S, van Roosmalen, Markus J, van Lieshout, Stef, Nijman, Isaac J, Roessingh, Wijnand, van 't Slot, Ruben, van de Belt, José, Guryev, Victor, Koudijs, Marco, Voest, Emile, Cuppen, Edwin
Published 2011

Genome-wide patterns and properties of de novo mutations in humans

by Francioli, Laurent C., Polak, Paz P., Koren, Amnon, Menelaou, Androniki, Chun, Sung, Renkens, Ivo, van Duijn, Cornelia M., Swertz, Morris, Wijmenga, Cisca, van Ommen, Gertjan, Slagboom, P. Eline, Boomsma, Dorret I., Ye, Kai, Guryev, Victor, Arndt, Peter F., Kloosterman, Wigard P., de Bakker, Paul I. W., Sunyaev, Shamil R.
Published 2015

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

by Hehir-Kwa, Jayne Y., Marschall, Tobias, Kloosterman, Wigard P., Francioli, Laurent C., Baaijens, Jasmijn A., Dijkstra, Louis J., Abdellaoui, Abdel, Koval, Vyacheslav, Thung, Djie Tjwan, Wardenaar, René, Renkens, Ivo, Coe, Bradley P., Deelen, Patrick, de Ligt, Joep, Lameijer, Eric-Wubbo, van Dijk, Freerk, Hormozdiari, Fereydoun, Uitterlinden, André G., van Duijn, Cornelia M., Eichler, Evan E., de Bakker, Paul I. W., Swertz, Morris A., Wijmenga, Cisca, van Ommen, Gert-Jan B., Slagboom, P. Eline, Boomsma, Dorret I., Schönhuth, Alexander, Ye, Kai, Guryev, Victor
Published 2016

Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease

by van der Crabben, Saskia N., Hennus, Marije P., McGregor, Grant A., Ritter, Deborah I., Nagamani, Sandesh C.S., Wells, Owen S., Harakalova, Magdalena, Chinn, Ivan K., Alt, Aaron, Vondrova, Lucie, Hochstenbach, Ron, van Montfrans, Joris M., Terheggen-Lagro, Suzanne W., van Lieshout, Stef, van Roosmalen, Markus J., Renkens, Ivo, Duran, Karen, Nijman, Isaac J., Kloosterman, Wigard P., Hennekam, Eric, Orange, Jordan S., van Hasselt, Peter M., Wheeler, David A., Palecek, Jan J., Lehmann, Alan R., Oliver, Antony W., Pearl, Laurence H., Plon, Sharon E., Murray, Johanne M., van Haaften, Gijs
Published 2016