Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase

by Zhang, Ji, Yan, Yi-Jun, An, Jing, Huang, Sheng-Xiong, Wang, Xiang-Jing, Xiang, Wen-Sheng
Published 2015

Enediyne Polyketide Synthases Stereoselectively Reduce the β-Ketoacyl Intermediates to β-d-Hydroxyacyl Intermediates in Enediyne Core Biosynthesis

by Ge, Hui-Ming, Huang, Tingting, Rudolf, Jeffrey D., Lohman, Jeremy R., Huang, Sheng-Xiong, Guo, Xun, Shen, Ben
Published 2014

Cycloheximide and Actiphenol Production in Streptomyces sp. YIM56141 Governed by Single Biosynthetic Machinery Featuring an Acyltransferase-less Type I Polyketide Synthase

by Yin, Min, Yan, Yijun, Lohman, Jeremy R., Huang, Sheng-Xiong, Ma, Ming, Zhao, Guang-Rong, Xu, Li-Hua, Xiang, Wensheng, Shen, Ben
Published 2014

Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids

by Yan, Yijun, Yang, Jing, Yu, Zhiyin, Yu, Mingming, Ma, Ya-Tuan, Wang, Li, Su, Can, Luo, Jianying, Horsman, Geoffrey P., Huang, Sheng-Xiong
Published 2016

Biosynthetic Potential-Based Strain Prioritization for Natural Product Discovery: A Showcase for Diterpenoid-Producing Actinomycetes

by Xie, Pengfei, Ma, Ming, Rateb, Mostafa E., Shaaban, Khaled A., Yu, Zhiguo, Huang, Sheng-Xiong, Zhao, Li-Xing, Zhu, Xiangcheng, Yan, Yijun, Peterson, Ryan M., Lohman, Jeremy R., Yang, Dong, Yin, Min, Rudolf, Jeffrey D., Jiang, Yi, Duan, Yanwen, Shen, Ben
Published 2014