A highly efficient cocaine detoxifying enzyme obtained by computational design

by Zheng, Fang, Xue, Liu, Hou, Shurong, Liu, Junjun, Zhan, Max, Yang, Wenchao, Zhan, Chang-Guo
Published 2014

Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse

by Wang, Guojun, Zhang, Ting, Huang, Haifeng, Hou, Shurong, Chen, Xiabin, Zheng, Fang, Zhan, Chang-Guo
Published 2016

Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification

by Fang, Lei, Chow, K. Martin, Hou, Shurong, Xue, Liu, Chen, Xiabin, Rodgers, David W., Zheng, Fang, Zhan, Chang-Guo
Published 2014

Gene Transfer of Mutant Mouse Cholinesterase Provides High Lifetime Expression and Reduced Cocaine Responses with No Evident Toxicity

by Geng, Liyi, Gao, Yang, Chen, Xiabin, Hou, Shurong, Zhan, Chang-Guo, Radic, Zoran, Parks, Robin J., Russell, Stephen J., Pham, Linh, Brimijoin, Stephen
Published 2013