A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models

by Spangler, Benjamin, Fontaine, Shaun D., Shi, Yihui, Sambucetti, Lidia, Mattis, Aras N., Hann, Byron, Wells, James A., Renslo, Adam R.
Published 2016

A tumor suppressing function in the epithelial adhesion protein Trask

by Spassov, Danislav S., Wong, Ching Hang, Harris, Geoffrey, McDonough, Stephen, Phojanakong, Paul, Wang, Donghui, Hann, Byron, Bazarov, Alexey V., Yaswen, Paul, Khanafshar, Elham, Moasser, Mark M.
Published 2011

Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors

by Ducker, Gregory S., Atreya, Chloe E., Simko, Jeffry P., Hom, Yun K., Matli, Mary R., Benes, Cyril H., Hann, Byron, Nakakura, Eric K., Bergsland, Emily K., Donner, David B., Settleman, Jeffrey, Shokat, Kevan M., Warren, Robert S.
Published 2013

TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response

by Rozanov, Dmitri, Cheltsov, Anton, Sergienko, Eduard, Vasile, Stefan, Golubkov, Vladislav, Aleshin, Alexander E., Levin, Trevor, Traer, Elie, Hann, Byron, Freimuth, Julia, Alexeev, Nikita, Alekseyev, Max A., Budko, Sergey P, Bächinger, Hans Peter, Spellman, Paul
Published 2015

Pharmacological brake-release of mRNA translation enhances cognitive memory

by Sidrauski, Carmela, Acosta-Alvear, Diego, Khoutorsky, Arkady, Vedantham, Punitha, Hearn, Brian R, Li, Han, Gamache, Karine, Gallagher, Ciara M, Ang, Kenny K-H, Wilson, Chris, Okreglak, Voytek, Ashkenazi, Avi, Hann, Byron, Nader, Karim, Arkin, Michelle R, Renslo, Adam R, Sonenberg, Nahum, Walter, Peter
Published 2013