Depletion of eIF2.GTP.Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo

by Aktas, Bertal H., Bordelois, Paula, Peker, Selen, Merajver, Sophia, Halperin, Jose A.
Published 2015

Small-molecule targeting of translation initiation for cancer therapy

by Aktas, Bertal H., Qiao, Yuan, Ozdelen, Esra, Schubert, Roland, Sevinc, Sema, Harbinski, Fred, Grubissich, Luciano, Singer, Samuel, Halperin, Jose A.
Published 2013

Chemical Genetics Identify eIF2α Kinase Heme Regulated Inhibitor as Anti-Cancer Target

by Chen, Ting, Ozel, Duygu, Qiao, Yuan, Harbinski, Fred, Chen, Limo, Denoyelle, Séverine, He, Xiaoying, Zvereva, Nela, Supko, Jeffrey G., Chorev, Michael, Halperin, Jose A., Aktas, Bertal H.
Published 2011

Synthesis of Rigidified eIF4E/eIF4G Inhibitor-1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction

by Mahalingam, Poornachandran, Takrouri, Khuloud, Chen, Ting, Sahoo, Rupam, Papadopoulos, Evangelos, Chen, Limo, Wagner, Gerhard, Aktas, Bertal H., Halperin, Jose A., Chorev, Michael
Published 2014

Tumor suppression by small molecule inhibitors of translation initiation

by Chen, Limo, Aktas, Bertal H, Wang, Yibo, He, Xiaoying, Sahoo, Rupam, Zhang, Nancy, Denoyelle, Severine, Kabha, Eihab, Yang, Hongwei, Freedman, Revital Yefidoff, Supko, Jeffrey G, Chorev, Michael, Wagner, Gerhard, Halperin, Jose A
Published 2012