Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

by Holler, Marina, Grottke, Astrid, Mueck, Katharina, Manes, Julia, Jücker, Manfred, Rodemann, H. Peter, Toulany, Mahmoud
Published 2016

Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma

by Ewald, Florian, Nörz, Dominik, Grottke, Astrid, Bach, Johanna, Herzberger, Christiane, Hofmann, Bianca T., Nashan, Björn, Jücker, Manfred
Published 2015

Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4

by Grottke, Astrid, Ewald, Florian, Lange, Tobias, Nörz, Dominik, Herzberger, Christiane, Bach, Johanna, Grabinski, Nicole, Gräser, Lareen, Höppner, Frank, Nashan, Björn, Schumacher, Udo, Jücker, Manfred
Published 2016