A Role for Msh6 But Not Msh3 in Somatic Hypermutation and Class Switch Recombination

by Martomo, Stella A., Yang, William W., Gearhart, Patricia J.
Published 2004

Exceptional Antibodies Produced by Successive Immunizations

by Gearhart, Patricia J., Castiblanco, Diana P., Russell Knode, Lisa M.
Published 2015

Absence of DNA Polymerase η Reveals Targeting of C Mutations on the Nontranscribed Strand in Immunoglobulin Switch Regions

by Zeng, Xianmin, Negrete, George A., Kasmer, Cynthia, Yang, William W., Gearhart, Patricia J.
Published 2004

Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein

by Phung, Quy H., Winter, David B., Cranston, Aaron, Tarone, Robert E., Bohr, Vilhelm A., Fishel, Richard, Gearhart, Patricia J.
Published 1998

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions

by Saribasak, Huseyin, Maul, Robert W., Cao, Zheng, Yang, William W., Schenten, Dominik, Kracker, Sven, Gearhart, Patricia J.
Published 2012

129-derived Strains of Mice Are Deficient in DNA Polymerase ι and Have Normal Immunoglobulin Hypermutation

by McDonald, John P., Frank, Ekaterina G., Plosky, Brian S., Rogozin, Igor B., Masutani, Chikahide, Hanaoka, Fumio, Woodgate, Roger, Gearhart, Patricia J.
Published 2003

MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes

by Wilson, Teresa M., Vaisman, Alexandra, Martomo, Stella A., Sullivan, Patsa, Lan, Li, Hanaoka, Fumio, Yasui, Akira, Woodgate, Roger, Gearhart, Patricia J.
Published 2005

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes

by Saribasak, Huseyin, Maul, Robert W., Cao, Zheng, McClure, Rhonda L., Yang, William, McNeill, Daniel R., Wilson, David M., Gearhart, Patricia J.
Published 2011

Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo–activated cells

by Maul, Robert W., Cao, Zheng, Venkataraman, Lakshmi, Giorgetti, Carol A., Press, Joan L., Denizot, Yves, Du, Hansen, Sen, Ranjan, Gearhart, Patricia J.
Published 2014

Immunoglobulin Class Switch Recombination Is Impaired in Atm-deficient Mice

by Lumsden, Joanne M., McCarty, Thomas, Petiniot, Lisa K., Shen, Rhuna, Barlow, Carrolee, Wynn, Thomas A., Morse, Herbert C., Gearhart, Patricia J., Wynshaw-Boris, Anthony, Max, Edward E., Hodes, Richard J.
Published 2004

DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes

by Maul, Robert W., MacCarthy, Thomas, Frank, Ekaterina G., Donigan, Katherine A., McLenigan, Mary P., Yang, William, Saribasak, Huseyin, Huston, Donald E., Lange, Sabine S., Woodgate, Roger, Gearhart, Patricia J.
Published 2016