Life in lights: Tracking mitochondrial delivery to lysosomes in vivo

by McWilliams, Thomas G., Ganley, Ian G.
Published 2016

A syntaxin 10–SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

by Ganley, Ian G., Espinosa, Eric, Pfeffer, Suzanne R.
Published 2008

Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling

by Reddy, Jonathan V., Ganley, Ian G., Pfeffer, Suzanne R.
Published 2006

Loss of iron triggers PINK1/Parkin-independent mitophagy

by Allen, George F G, Toth, Rachel, James, John, Ganley, Ian G
Published 2013

mTOR activates the VPS34–UVRAG complex to regulate autolysosomal tubulation and cell survival

by Munson, Michael J, Allen, George FG, Toth, Rachel, Campbell, David G, Lucocq, John M, Ganley, Ian G
Published 2015

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

by Stretton, Clare, Hoffmann, Thorsten M., Munson, Michael J., Prescott, Alan, Taylor, Peter M., Ganley, Ian G., Hundal, Harinder S.
Published 2015

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy*

by Petherick, Katy J., Conway, Owen J. L., Mpamhanga, Chido, Osborne, Simon A., Kamal, Ahmad, Saxty, Barbara, Ganley, Ian G.
Published 2015

Coibamide A Induces mTOR-Independent Autophagy and Cell Death in Human Glioblastoma Cells

by Hau, Andrew M., Greenwood, Jeffrey A., Löhr, Christiane V., Serrill, Jeffrey D., Proteau, Philip J., Ganley, Ian G., McPhail, Kerry L., Ishmael, Jane E.
Published 2013

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

by McWilliams, Thomas G., Prescott, Alan R., Allen, George F.G., Tamjar, Jevgenia, Munson, Michael J., Thomson, Calum, Muqit, Miratul M.K., Ganley, Ian G.
Published 2016

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III pho...

by Bago, Ruzica, Malik, Nazma, Munson, Michael J., Prescott, Alan R., Davies, Paul, Sommer, Eeva, Shpiro, Natalia, Ward, Richard, Cross, Darren, Ganley, Ian G., Alessi, Dario R.
Published 2014

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

by MacCallum, Stephanie F., Groves, Michael J., James, John, Murray, Karen, Appleyard, Virginia, Prescott, Alan R., Drbal, Abed A., Nicolaou, Anna, Cunningham, Joan, Haydock, Sally, Ganley, Ian G., Westwood, Nicholas J., Coates, Philip J., Lain, Sonia, Tauro, Sudhir
Published 2013