Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells

by Deng, Peter, Torrest, Audrey, Pollock, Kari, Dahlenburg, Heather, Annett, Geralyn, Nolta, Jan A., Fink, Kyle D.
Published 2016

Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

by Fink, Kyle D, Rossignol, Julien, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Bavar, Angela M, Clerc, Steven, Lowrance, Steven A, Song, Cheng, Lescaudron, Laurent, Dunbar, Gary L
Published 2013

Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is depe...

by Rossignol, Julien, Fink, Kyle D, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Clerc, Steven, Bavar, Angela M, Lowrance, Steven A, Song, Cheng, Witte, Steven, Lescaudron, Laurent, Dunbar, Gary L
Published 2015

Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models

by Pollock, Kari, Dahlenburg, Heather, Nelson, Haley, Fink, Kyle D, Cary, Whitney, Hendrix, Kyle, Annett, Geralyn, Torrest, Audrey, Deng, Peter, Gutierrez, Joshua, Nacey, Catherine, Pepper, Karen, Kalomoiris, Stefanos, D Anderson, Johnathon, McGee, Jeannine, Gruenloh, William, Fury, Brian, Bauer, Gerhard, Duffy, Alexandria, Tempkin, Theresa, Wheelock, Vicki, Nolta, Jan A
Published 2016