High thioredoxin-1 levels in rheumatoid arthritis patients diminish binding and signalling of the monoclonal antibody Tregalizumab

by Heim, Katharina, Dälken, Benjamin, Faust, Stefanie, Rharbaoui, Faiza, Engling, Andre, Wallmeier, Holger, Dingermann, Theodor, Radeke, Heinfried H, Schüttrumpf, Jörg, Gutscher, Marcus
Published 2016

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

by Helling, Bianca, König, Martin, Dälken, Benjamin, Engling, Andre, Krömer, Wolfgang, Heim, Katharina, Wallmeier, Holger, Haas, Jürgen, Wildemann, Brigitte, Fritz, Brigitte, Jonuleit, Helmut, Kubach, Jan, Dingermann, Theodor, Radeke, Heinfried H, Osterroth, Frank, Uherek, Christoph, Czeloth, Niklas, Schüttrumpf, Jörg
Published 2015