The PI3K inhibitor taselisib overcomes letrozole resistance in a breast cancer model expressing aromatase

by Hoeflich, Klaus P., Guan, Jane, Edgar, Kyle A., O'Brien, Carol, Savage, Heidi, Wilson, Timothy R., Neve, Richard M., Friedman, Lori S., Wallin, Jeffrey J.
Published 2016

Amphiregulin and PTEN evoke a multimodal mechanism of acquired resistance to PI3K inhibition

by Edgar, Kyle A., Crocker, Lisa, Cheng, Eric, Wagle, Marie-Claire, Wongchenko, Matthew, Yan, Yibing, Wilson, Timothy R., Dompe, Nicholas, Neve, Richard M., Belvin, Marcia, Sampath, Deepak, Friedman, Lori S., Wallin, Jeffrey J.
Published 2014

Active PI3K Pathway Causes an Invasive Phenotype Which Can Be Reversed or Promoted by Blocking the Pathway at Divergent Nodes

by Wallin, Jeffrey J., Guan, Jane, Edgar, Kyle A., Zhou, Wei, Francis, Ross, Torres, Anthony C., Haverty, Peter M., Eastham-Anderson, Jeffrey, Arena, Sabrina, Bardelli, Alberto, Griffin, Sue, Goodall, John E., Grimshaw, Kyla M., Hoeflich, Klaus P., Torrance, Christopher, Belvin, Marcia, Friedman, Lori S.
Published 2012