Targeting the TAM Receptors in Leukemia

by Huey, Madeline G., Minson, Katherine A., Earp, H. Shelton, DeRyckere, Deborah, Graham, Douglas K.
Published 2016

Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus

by Migdall-Wilson, Justine, Bates, Christine, Schlegel, Jennifer, Brandão, Luis, Linger, Rachel M. A., DeRyckere, Deborah, Graham, Douglas K.
Published 2012

Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission

by Christoph, Sandra, Schlegel, Jennifer, Alvarez-Calderon, Francesca, Kim, Yong-Mi, Brandao, Luis N, DeRyckere, Deborah, Graham, Douglas K
Published 2013

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer

by Cummings, Christopher T., Linger, Rachel M.A., Cohen, Rebecca A., Sather, Susan, Kirkpatrick, Gregory D., Davies, Kurtis D., DeRyckere, Deborah, Earp, H. Shelton, Graham, Douglas K.
Published 2014

Mer or Axl Receptor Tyrosine Kinase Inhibition Promotes Apoptosis, Blocks Growth, and Enhances Chemosensitivity of Human Non-Small Cell Lung Cancer

by Linger, Rachel M.A., Cohen, Rebecca A., Cummings, Christopher T., Sather, Susan, Migdall-Wilson, Justine, Middleton, Deryck H.G., Lu, Xian, Barón, Anna E., Franklin, Wilbur A., Merrick, Daniel T., Jedlicka, Paul, DeRyckere, Deborah, Heasley, Lynn E., Graham, Douglas K.
Published 2012

MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme

by Sufit, Alexandra, Lee-Sherick, Alisa B., DeRyckere, Deborah, Rupji, Manali, Dwivedi, Bhakti, Varella-Garcia, Marileila, Pierce, Angela M., Kowalski, Jeanne, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Keating, Amy K., Graham, Douglas K.
Published 2016

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia

by Lee-Sherick, Alisa B., Zhang, Weihe, Menachof, Kelly K., Hill, Amanda A., Rinella, Sean, Kirkpatrick, Gregory, Page, Lauren S., Stashko, Michael A., Jordan, Craig T., Wei, Qi, Liu, Jing, Zhang, Dehui, DeRyckere, Deborah, Wang, Xiaodong, Frye, Stephen, Earp, H. Shelton, Graham, Douglas K.
Published 2015

UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor

by Zhang, Weihe, DeRyckere, Deborah, Hunter, Debra, Liu, Jing, Stashko, Michael A., Minson, Katherine A., Cummings, Christopher T., Lee, Minjung, Glaros, Trevor G., Newton, Dianne L., Sather, Susan, Zhang, Dehui, Kireev, Dmitri, Janzen, William P., Earp, H. Shelton, Graham, Douglas K., Frye, Stephen V., Wang, Xiaodong
Published 2014