A method for quantification of exportin-1 (XPO1) occupancy by Selective Inhibitor of Nuclear Export (SINE) compounds

by Crochiere, Marsha L., Baloglu, Erkan, Klebanov, Boris, Donovan, Scott, del Alamo, Diego, Lee, Margaret, Kauffman, Michael, Shacham, Sharon, Landesman, Yosef
Published 2015

Deciphering mechanisms of drug sensitivity and resistance to Selective Inhibitor of Nuclear Export (SINE) compounds

by Crochiere, Marsha, Kashyap, Trinayan, Kalid, Ori, Shechter, Sharon, Klebanov, Boris, Senapedis, William, Saint-Martin, Jean-Richard, Landesman, Yosef
Published 2015

Selinexor, a selective inhibitor of nuclear export (SINE), shows enhanced activity in combination with PD-1/PD-L1 blockade in syngeneic murine models of colon cancer and melanoma

by Farren, Matthew R, Shakya, Reena, Hennessey, Rebecca, Mace, Thomas, Yang, Jennifer, Elnaggar, Omar, Young, Gregory, Landesman, Yosef, Carlson, Robert, Elloul, Sivan, Crochiere, Marsha, Burd, Christin, Lesinski, Gregory
Published 2015