Biodistribution of neutralizing monoclonal antibodies IgG1 b12 and LALA in mucosal and lymphatic tissues of rhesus macaques

by Hessell, AJ, Epson, E, Moldt, B, Rakasz, E, Pandey, S, Sutton, WF, Brower, Z, Hirsch, VM, Burton, DR, Haigwood, NL
Published 2012

MAb PGT121 protects against mucosal SHIV challenge in macaques at concentrations corresponding to its highly potent in vitro neutralization capacity

by Moldt, B, Rakasz, EG, Schultz, N, Chan-Hui, P, Swiderek, K, Watkins, DI, Burton, DR, Poignard, P
Published 2012

Structural comparison of somatically related PG9 and PG16 in complex with their epitope reveals differences in glycan recognition

by Pancera, M, McLellan, JS, Shahzad-ul-Hussan, S, Doria-Rose, N, Zhang, B, Yang, Y, Burton, DR, Koff, WC, Bewley, CA, Kwong, PD
Published 2012

Rational immunogen design to target specific germline B cell receptors

by Jardine, J, Kalyuzhniy, O, Ota, T, McGuire, A, Menis, S, Julien, J, Falkowska, E, MacPherson, S, Jones, M, Burton, DR, Wilson, IA, Stamatatos, L, Nemazee, D, Schief, WR
Published 2012

Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies

by Julien, J, Kong, L, Pejchal, R, Khayat, R, Lee, J, Stanfield, RS, Walker, LM, Doores, KJ, Folkowska, E, Poignard, P, Depetris, R, Sanders, RW, Koff, WC, Moore, JP, Ward, AB, Burton, DR, Wilson, IA
Published 2012

Engineered mice and B cell lines expressing broadly neutralizing antibodies and their unmutated precursors: tools for HIV vaccinology

by Nemazee, D, Doyle-Cooper, C, Ota, T, Cooper, AB, Huber, M, Falkowska, E, Doores, K, Hangartner, L, Le, K, Sok, D, Jardine, J, Lifson, J, Wu, X, Mascola, JR, Poignard, P, Binley, JM, Chakrabarti, BK, Schief, WR, Wyatt, RT, Burton, DR
Published 2012

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies

by Doria-Rose, NA, Georgiev, I, Staupe, RP, O'Dell, S, Chuang, G, Gorman, J, McLellan, JS, Pancera, M, Bonsignori, M, Haynes, BF, Burton, DR, Koff, WC, Kwong, PD, Mascola, JR
Published 2012