Telomere, telomerase and liver disease

by Aravinthan, Aloysious D., Alexander, Graeme J.
Published 2017

γ-H2AX + CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infection

by Hoare, Matthew, Shankar, Arun, Shah, Meera, Rushbrook, Simon, Gelson, William, Davies, Susan, Akbar, Arne, Alexander, Graeme J.M.
Published 2013

Persistence of Hepatitis C Virus Traces after Spontaneous Resolution of Hepatitis C

by Chen, Annie Y., Hoare, Matthew, Shankar, Arun N., Allison, Michael, Alexander, Graeme J. M., Michalak, Tomasz I.
Published 2015

Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease

by Aravinthan, Aloysious, Pietrosi, Giada, Hoare, Matthew, Jupp, James, Marshall, Aileen, Verrill, Clare, Davies, Susan, Bateman, Adrian, Sheron, Nick, Allison, Michael, Alexander, Graeme J. M.
Published 2013

Correction: Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis

by Tachtatzis, Phaedra M., Marshall, Aileen, Aravinthan, Aloysious, Verma, Suman, Penrhyn-Lowe, Sue, Mela, Marianna, Scarpini, Cinzia, Davies, Susan E., Coleman, Nicholas, Alexander, Graeme J. M.
Published 2015

Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis

by Tachtatzis, Phaedra M., Marshall, Aileen, Aravinthan, Aloysius, Verma, Suman, Penrhyn-Lowe, Sue, Mela, Marianna, Scarpini, Cinzia, Davies, Susan E., Coleman, Nicholas, Alexander, Graeme J. M.
Published 2015

A Viral Discovery Methodology for Clinical Biopsy Samples Utilising Massively Parallel Next Generation Sequencing

by Daly, Gordon M., Bexfield, Nick, Heaney, Judith, Stubbs, Sam, Mayer, Antonia P., Palser, Anne, Kellam, Paul, Drou, Nizar, Caccamo, Mario, Tiley, Laurence, Alexander, Graeme J. M., Bernal, William, Heeney, Jonathan L.
Published 2011

BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial

by Hegade, Vinod S., Kendrick, Stuart F. W., Dobbins, Robert L., Miller, Sam R., Richards, Duncan, Storey, James, Dukes, George, Gilchrist, Kim, Vallow, Susan, Alexander, Graeme J., Corrigan, Margaret, Hirschfield, Gideon M., Jones, David E. J.
Published 2016

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

by Sampaziotis, Fotios, Cardoso de Brito, Miguel, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A.C., Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H., Bradley, J. Andrew, Gelson, William T.H., Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J., Hannan, Nicholas R.F., Vallier, Ludovic
Published 2015

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

by Mells, George F., Floyd, James A.B., Morley, Katherine I., Cordell, Heather J., Franklin, Christopher S., Shin, So-Youn, Heneghan, Michael A., Neuberger, James M., Donaldson, Peter T., Day, Darren B., Ducker, Samantha J., Muriithi, Agnes W., Wheater, Elizabeth F., Hammond, Christopher J., Dawwas, Muhammad F., Jones, David E., Peltonen, Leena, Alexander, Graeme J., Sandford, Richard N., Anderson, Carl A.
Published 2011

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

by Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M., Donaldson, Peter T, Bathgate, Andrew J, Burroughs, Andrew, Davies, Mervyn H, Jones, David E, Alexander, Graeme J, Barrett, Jeffrey C, Sandford, Richard N, Anderson, Carl A
Published 2012

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

by Sampaziotis, Fotios, de Brito, Miguel Cardoso, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A. C., Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H., Bradley, J. Andrew, Gelson, William TH, Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J., Hannan, Nicholas R.F., Vallier, Ludovic
Published 2015

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

by Liu, Yang-Lin, Reeves, Helen L., Burt, Alastair D., Tiniakos, Dina, McPherson, Stuart, Leathart, Julian B. S., Allison, Michael E. D., Alexander, Graeme J., Piguet, Anne-Christine, Anty, Rodolphe, Donaldson, Peter, Aithal, Guruprasad P., Francque, Sven, Van Gaal, Luc, Clement, Karine, Ratziu, Vlad, Dufour, Jean-Francois, Day, Christopher P., Daly, Ann K., Anstee, Quentin M.
Published 2014

Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody

by Tan, Lu, Perez, Juan, Mela, Marianna, Miranda, Elena, Burling, Keith A, Rouhani, Farshid N, DeMeo, Dawn L, Haq, Imran, Irving, James A, Ordóñez, Adriana, Dickens, Jennifer A, Brantly, Mark, Marciniak, Stefan J, Alexander, Graeme J M, Gooptu, Bibek, Lomas, David A
Published 2015

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

by Sampaziotis, Fotios, Justin, Alexander W., Tysoe, Olivia C., Sawiak, Stephen, Godfrey, Edmund M., Upponi, Sara S., Gieseck, Richard L., de Brito, Miguel Cardoso, Berntsen, Natalie Lie, Gómez-Vázquez, María J., Ortmann, Daniel, Yiangou, Loukia, Ross, Alexander, Bargehr, Johannes, Bertero, Alessandro, Zonneveld, Mariëlle C.F., Pedersen, Marianne T., Pawlowski, Matthias, Valestrand, Laura, Madrigal, Pedro, Georgakopoulos, Nikitas, Pirmadjid, Negar, Skeldon, Gregor M., Casey, John, Shu, Wenmiao, Materek, Paulina M., Snijders, Kirsten, Brown, Stephanie, Rimland, Casey A., Simonic, Ingrid, Davies, Susan E., Jensen, Kim B., Zilbauer, Matthias, Gelson, William T.H., Alexander, Graeme J., Sinha, Sanjay, Hannan, Nicholas R.F., Wynn, Thomas A., Karlsen, Tom H., Melum, Espen, Markaki, Athina E., Saeb-Parsy, Kourosh, Vallier, Ludovic
Published 2017