Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer

by Adams, Peter D., Jasper, Heinrich, Rudolph, K. Lenhard
Published 2015

Critical Parameters for Efficient Sonication and Improved Chromatin Immunoprecipitation of High Molecular Weight Proteins

by Pchelintsev, Nikolay A., Adams, Peter D., Nelson, David M.
Published 2016

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells

by Maddocks, Oliver D.K., Labuschagne, Christiaan F., Adams, Peter D., Vousden, Karen H.
Published 2016

Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex

by Daniel Ricketts, M, Frederick, Brian, Hoff, Henry, Tang, Yong, Schultz, David C., Singh Rai, Taranjit, Grazia Vizioli, Maria, Adams, Peter D., Marmorstein, Ronen
Published 2015

DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML

by Lund, Kirstin, Cole, John J, VanderKraats, Nathan D, McBryan, Tony, Pchelintsev, Nikolay A, Clark, William, Copland, Mhairi, Edwards, John R, Adams, Peter D
Published 2014

Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitm...

by Howard, Lynsey, Mackenzie, Ruth M, Pchelintsev, Nikolay A, McBryan, Tony, McClure, John D, McBride, Martin W, Kane, Nicole M, Adams, Peter D, Milligan, Graeme, Baker, Andrew H
Published 2013

Lysosome-mediated processing of chromatin in senescence

by Ivanov, Andre, Pawlikowski, Jeff, Manoharan, Indrani, van Tuyn, John, Nelson, David M., Rai, Taranjit Singh, Shah, Parisha P., Hewitt, Graeme, Korolchuk, Viktor I., Passos, Joao F., Wu, Hong, Berger, Shelley L., Adams, Peter D.
Published 2013

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling

by Pawlikowski, Jeffrey S, Brock, Claire, Chen, Sheau-Chiann, Al-Olabi, Lara, Nixon, Colin, McGregor, Fiona, Paine, Simon, Chanudet, Estelle, Lambie, Wendy, Holmes, William M, Mullin, James M, Richmond, Ann, Wu, Hong, Blyth, Karen, King, Ayala, Kinsler, Veronica A, Adams, Peter D
Published 2015

Autophagy mediates degradation of nuclear lamina

by Dou, Zhixun, Xu, Caiyue, Donahue, Greg, Shimi, Takeshi, Pan, Ji-An, Zhu, Jiajun, Ivanov, Andrejs, Capell, Brian C., Drake, Adam M., Shah, Parisha P., Catanzaro, Joseph M., Ricketts, M. Daniel, Lamark, Trond, Adam, Stephen A., Marmorstein, Ronen, Zong, Wei-Xing, Johansen, Terje, Goldman, Robert D., Adams, Peter D., Berger, Shelley L.
Published 2015

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigen...

by Nelson, David M., Jaber-Hijazi, Farah, Cole, John J., Robertson, Neil A., Pawlikowski, Jeffrey S., Norris, Kevin T., Criscione, Steven W., Pchelintsev, Nikolay A., Piscitello, Desiree, Stong, Nicholas, Rai, Taranjit Singh, McBryan, Tony, Otte, Gabriel L., Nixon, Colin, Clark, William, Riethman, Harold, Wu, Hong, Schotta, Gunnar, Garcia, Benjamin A., Neretti, Nicola, Baird, Duncan M., Berger, Shelley L., Adams, Peter D.
Published 2016

Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest

by Dikovskaya, Dina, Cole, John J., Mason, Susan M., Nixon, Colin, Karim, Saadia A., McGarry, Lynn, Clark, William, Hewitt, Rachael N., Sammons, Morgan A., Zhu, Jiajun, Athineos, Dimitris, Leach, Joshua D.G., Marchesi, Francesco, van Tuyn, John, Tait, Stephen W., Brock, Claire, Morton, Jennifer P., Wu, Hong, Berger, Shelley L., Blyth, Karen, Adams, Peter D.
Published 2015

Mitochondria are required for pro‐ageing features of the senescent phenotype

by Correia‐Melo, Clara, Marques, Francisco DM, Anderson, Rhys, Hewitt, Graeme, Hewitt, Rachael, Cole, John, Carroll, Bernadette M, Miwa, Satomi, Birch, Jodie, Merz, Alina, Rushton, Michael D, Charles, Michelle, Jurk, Diana, Tait, Stephen WG, Czapiewski, Rafal, Greaves, Laura, Nelson, Glyn, Bohlooly‐Y, Mohammad, Rodriguez‐Cuenca, Sergio, Vidal‐Puig, Antonio, Mann, Derek, Saretzki, Gabriele, Quarato, Giovanni, Green, Douglas R, Adams, Peter D, von Zglinicki, Thomas, Korolchuk, Viktor I, Passos, João F
Published 2016