Successful drug discovery

Bibliographic Details
Other Authors: Fischer, Janos (Editor), Rotella, David P. (Editor)
Format: Book
Language:English
Published: Weinheim, Germany : Wiley-VCH 2015
Subjects:
Table of Contents:
  • 1. Serendipitous target-based drug discoveries
  • 2. Drug discoveries and molecular mechanism of action
  • 3. Insulin analogs improving the therapy of diabetes
  • 4. The discovery of Stendra (Avanafil) for the Treatment of Erectile Dysfunction
  • 5. Dapagliflozin, a selective SGLT2 inhibitor for treatment of diabetes
  • 6. Elvitegravir, a new HIV-1 integrase inhibitor for antiretroviral therapy
  • 7. Discovery of linagliptin for the treatment of type 2 diabetes mellitus
  • 8. The discovery of Alimta (Pemetrexed)
  • 9. Perampanel: A novel, noncompetitive AMPA receptor antagonist for the treatment of epilepsy
  • 10. Discovery and development of telaprevir (Incivek ) a protease inhibitor to treat hepatitis C infection
  • 11. Antibody drug conjugates: design and development of trastuzumab emtansine (T-DM1)