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00000cam a2200000 7i4500 |
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20170829093000.0 |
| 008 |
170601s2015 -uk eng |
| 020 |
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|a 1849738254
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| 020 |
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|a 9781849738255
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| 050 |
0 |
0 |
|a RM301.25
|b .H86 2015
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| 060 |
1 |
0 |
|a W 20.55.T7
|b .H918 2015
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| 090 |
0 |
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|a RM301.25
|b .H86 2015
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| 245 |
0 |
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|a Human-based systems for translational research
|c Robert Coleman
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| 260 |
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|a Cambridge :
|b The Royal Society of Chemistry ,
|c 2015
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| 300 |
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|a xvii, 278 p. :
|b ill.(some col.) ;
|c 24 cm.
|
| 440 |
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|a RSC drug discovery series
|v no. 41
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| 504 |
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|a Includes bibliographical references (p. 262-266) and index
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| 505 |
0 |
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|a 1. Access to human cells and tissues -- 2. Functional studies with human isolated tissues to better predict clinical safety and efficacy -- 3. Translational research in pharmacology and toxicology using precision-cut tissue slices -- 4. Modelling the human respiratory system: Approaches for in vitro safety testing and drug discovery -- 5. Complex primary human cell systems for drug discovery -- 6. Human in vitro ADMET and prediction of human pharmacokinetics and toxicity liabilities at the discovery stage -- 7. Body-on-a-chip technology and suporting -- 8. Utility of human stem cells for drug discovery -- 9. In silico solutions for predicting efficacy and toxicity -- 10. In silico organ modelling in predicting efficacy and safety of new medicines -- 11. Human microdosing/phase 0 studies to accelerate drug development
|
| 650 |
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0 |
|a Drug development
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| 650 |
|
0 |
|a Human experimentation in medicine
|
| 650 |
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0 |
|a Tissue Engineering
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| 650 |
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0 |
|a Translational Medical Research
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| 700 |
1 |
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|a Coleman, Robert ,
|e author
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| 999 |
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|a 1000169163
|b Book
|c OPEN SHELF (30 DAYS)
|e Tembila Campus
|