Ion channel drug discovery
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge :
Royal Society of Chemistry ,
c2015
|
| Series: | RSC drug discovery series 39
|
| Subjects: |
Table of Contents:
- 1. Ion channel drug discovery: a historical perspective
- 2. High throughput screening
- 3. Automated electrophysiology in ion channel drug discovery
- 4. Structural understanding of ion channels in atomic detail
- 5. Voltages-gated Sodium Channels: structure, function, and molecular pharmacology
- 6. AMPA receptor positive allosteric modulators- a case history
- 7. The discovery of novel inhaled ENaC blockers for the treatment of cystic fibrosis lung disease
- 8. The therapeutic potential of small-molecule modulators of the cystic fibrosis transmembrane conductance regulator (CFTR) CI channel
- 9. TRPV1 antagonism: from research to clinic
- 10. Open access to the KCNQ channel: Retigabine and second generation M-current openers
- 11. The therapeutic potential of hERG1 K channels for treating cancer and cardiac arrhythmias
- 12. Does nature do Ion channel drug discovery better than us?
- 13. Antibodies as Ion channel modulators
- 14. Ion channel drug discovery: future perspectives