Introduction to drug disposition and pharmacokinetics
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| Format: | Book |
| Language: | English |
| Published: |
Chichester, West Sussex :
Wiley
2017
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Table of Contents:
- 1. Introduction: basic concepts
- 2. Drug administration and distribution
- 3. Drug metabolism and excretion
- 4. Single-compartment pharmacokinetic models
- 5. Multiple-compartment and non-compartment pharmacokinetic models
- 6. Kinetics of metabolism and excretion
- 7. Clearance, protein binding and physiological modelling
- 8. Quantitative pharmacological relationships
- 9. Pharmacokinetics of large molecules
- 10. Pharmacogenetics and pharmacogenomics
- 11. Additional factors affecting plasma concentrations
- 12. Effects of age and disease on drug disposition
- 13. Drug interactions and toxicity
- 14. Perspectives and prospects: Reflections on the past, present and future of drug disposition and pharmacokinetic