Drug discovery toxicology : from target assessment to translational biomarkers

Drug discovery toxicology : from target assessment to translational biomarkers

Bibliographic Details
Main Author: Will, Yvonne (Author)
Other Authors: Jeffy, Brandon D. (Editor), McDuffie, J. Eric (Editor), Olaharski, Andrew J. (Editor)
Format: Book
Language:English
Published: Hoboken, New Jersey : John Wiley & Sons c2016
Subjects:
Drug Discovery
Drugs > Testing
Drugs > Toxicology
High throughput screening (Drug development)
Toxicity testing
Table of Contents:
  • 1. Safety lead optimization strategies
  • 2. Basis for in vitro-in PK translation
  • 3. Predicting organ toxicity
  • 4. Addressing the false negative space-increasing predictivity
  • 5. Stem cells in toxicology
  • 5. Current status of preclinical in vivo toxicity biomarkers
  • 6. Kidney injury biomarkers
  • 7. Best practices in biomarker evaluations

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