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| 008 |
160404s2016 mau eng |
| 020 |
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|a 9780128036204
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| 050 |
0 |
0 |
|a RA1238
|b .C66 2016
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| 060 |
1 |
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|a QV 771
|b .C736 2016
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| 090 |
0 |
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|a RA1238
|b .C66 2016
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| 245 |
1 |
2 |
|a A comprehensive guide to toxicology in nonclinical drug development
|c Ali S. Faqi
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| 250 |
|
|
|a 2nd ed
|
| 260 |
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|a Boston, Massachusetts :
|b Elsevier ,
|c c2016
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| 300 |
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|a xiii, 971 p. :
|b ill. ;
|c 29 cm.
|
| 505 |
0 |
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|a 1. Drug discovery, metabolism, and pharmacokinetics -- 2. Toxicological studies and IND application, and first in-human clinical trial -- 3. Clinical pathology, histopathology, and biomarkers --
4. Biostatistics, regulatory toxicology, and role of study directors -- 5. Specialty route of administration -- 6. Nonclinical development of monoclonal antibodies, stem cells, oncogenic and non-oncogenic drugs, oligonucleotides, and vaccines -- 6. Safety evaluation of ocular drugs, botanical products, and medicinal devices -- 7. Predictive toxicology, toxicometabolomics, toxicogenomics, and imaging
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| 520 |
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|a This book is designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more
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| 650 |
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0 |
|a Clinical toxicology
|
| 650 |
|
0 |
|a Drug development
|
| 650 |
|
0 |
|a Drugs
|x Toxicology
|
| 650 |
|
0 |
|a Medical Pharmacology
|
| 700 |
1 |
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|a Faqi, Ali S. ,
|e author
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| 999 |
|
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|a 1000169211
|b Book
|c OPEN SHELF (30 DAYS)
|e Tembila Campus
|