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| LEADER |
00000cam a2200000 7i4500 |
| 001 |
0000091748 |
| 005 |
20170828.0 |
| 008 |
170530s2016 gw eng |
| 020 |
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|a 9783527339044
|
| 020 |
|
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|a 9783527694082
|
| 020 |
|
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|a 9783527694099
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| 020 |
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|a 9783527694105
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| 020 |
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|a 9783527694112
|
| 050 |
0 |
0 |
|a RC119
|b .C66 2016
|
| 060 |
1 |
0 |
|a QX 20
|b .C736 2016
|
| 090 |
0 |
0 |
|a RC119
|b .C66 2016
|
| 245 |
0 |
0 |
|a Comprehensive analysis of parasite biology :
|b from metabolism to drug discovery
|c edited by Sylke Muller, Rachel Cerdan, Ovidiu Radulescu
|
| 260 |
|
|
|a Weinheim, Germany :
|b Wiley-VCH ,
|c c2016
|
| 300 |
|
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|a Vol. 7, xxiv, 548 p. :
|b ill. (some col.) ;
|c 25 cm.
|
| 440 |
|
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|a Drug discovery in infectious diseases
|v volume 7
|
| 504 |
|
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|a Includes bibliographical references and index
|
| 505 |
0 |
|
|a 1. Discovery of the mechanism of action of novel compounds that target unicellular eukaryotic parasites -- 2. Antiparasitics from algae -- 3. Contribution of natural products to drug discovery in tropical diseases -- 4. Isoxazolines: a novel chemotype highly effective on ectoparasites -- 5. Trypanosomal cysteine peptidases: target validation and drug design strategies -- 6. Potential of pyrimidine metabolism for antitrypanosomal drug discovery -- 7. Phosphatidylcholine and phosphatidylethanolamine biosynthesis pathways in plasmodium -- 8. Immunophilins as possible drug targets in apicomplexan parasites -- 9. Targeting the Atg8 conjugation pathway for novel anti-apicomplexan drug discovery -- 10. Turnover of glycosomes in trypanosomes : perspectives for drug discovery -- 11. Glideosome of apicomplexans as a drug target -- 12. N-myristoyltransferase as a target for drug discovery in malaria -- 13. Methods to investigate metabolic systems in trypanosoma -- 14. The role of metabolomics in antiparasitic drug discovery -- 15. The importance of targeting lipid metabolism in parasites for drug discovery -- 16. Carbon metabolism of plasmodium falciparum -- 17. Epigenetic gene regulation: Key to development and survival of malaria parasites -- 18. Mechanisms regulating transcription in plasmodium falciparum as targets for novel antimalarial drugs -- 19. Aminoacyl t-RNA synthetases as antimalarial drug targets -- 20. Mathematical approaches to drug and target discovery. mathematical modeling and omic data integration to understand dynamic adaptation of apicomplexan parasites and identify pharmaceutical targets -- 21. Understanding protozoan parasite metabolism and identifying drug targets through constraint-based modeling -- 22. Attacking blood-borne parasites with mathematics
|
| 650 |
|
0 |
|a Medical parasitology
|
| 650 |
|
0 |
|a Parasites
|x Metabolism
|
| 650 |
|
0 |
|a Parasitic diseases
|
| 700 |
1 |
|
|a Cerdan, Rachel ,
|e author
|
| 700 |
1 |
|
|a Muller, Sylke ,
|e author
|
| 700 |
1 |
|
|a Radulescu, Ovidiu ,
|e author
|
| 999 |
|
|
|a 1000169197
|b Book
|c OPEN SHELF (30 DAYS)
|e Tembila Campus
|