Pharmaceutical amorphous solid dispersions - Newman, Ann (Hoboken, New Jersey : Wiley, 2015)
1. Introduction to amorphous solid dispersions -- 2. Polymers and surfactants -- 3. Amorphous solid dispersion screening -- 4. Solid state characterization of amorphous dispersions -- 5.
Physical stability and crystallization inhibition -- 6. Solubility and dissolution considerations for amorphous solid dispersions -- 7. Translational development of amorphous dispersions -- 8.
Preclinical and clinical studies -- 9. Spray-drying and scale-up -- 10. Hot melt extrusion of amorphous solid dispersions -- 11. Formulation development of amorphous dispersions -- 12. Scientific and regulatory considerations in product development -- 13. Chapter patenting amorphous solid dispersions of pharmaceuticals -- 14. Monographs on polymers and surfactants
Includes bibliographical references and index
Keywords: Absorption; Drug Carrier -- Pharmacokinetics; Drug delivery systems; Drugs -- Bioavailability; Drugs -- Solubility; Pharmacokinetics; Polymers -- Chemistry; Polymers -- Pharmacokinetics; Solubility; Technology, Pharmaceutical