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| 008 |
130909s2013 gw eng |
| 020 |
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|a 3527322027 (hardback : alk. paper)
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| 020 |
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|a 9783527322022 (hardback : alk. paper)
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| 020 |
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|a 9783527665402 (mobi)
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|a 9783527665419 (ePub)
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| 020 |
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|a 9783527665426 (ePDF)
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| 020 |
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|a 9783527665433 (oBook)
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| 050 |
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|a QH450
|b .P67 2013
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| 060 |
1 |
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|a QU 475
|b P855 2013
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| 090 |
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|a QU 475
|b P855 2013
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| 245 |
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|a Posttransciptional gene regulation :
|b RNA processing in
|c edited by Jane Wu
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| 260 |
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|a Weinheim, Germany :
|b Wiley-Blackwell ,
|c c2013
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| 300 |
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|a xvi, 260 p. :
|b ill. ;
|c 25 cm.
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| 504 |
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|a Includes bibliographical references and index
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| 505 |
0 |
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|a 1. The role of cotranscriptional recruitment of RNA-binding proteins in the maintenance of genomic stability -- 2. Transcription termination by RNA polymerase II -- 3. Posttranscriptional gene regulation by an editor : ADAR and its role in RNA editing -- 4. Posttranslational modification of Sm proteins : diverse roles in snRNP assembly and germ line specification -- 5. Structure, function, and biogenesis of small nucleolar ribonucleoprotein particles -- 6. Mechanistic insights into mammalian pre-mRNA splicing -- 7. Splicing decisions shape neuronal protein function across the transcriptome -- 8. Noncoding RNA : the major output of gene expression -- 9. Noncoding RNAs, neurodevelopment, and neurodegeneration -- 10. The evolution of the modern RNA world
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| 520 |
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|a Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry
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| 650 |
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0 |
|a Eukaryotic cells
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| 650 |
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0 |
|a Genetic regulation
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| 650 |
1 |
2 |
|a Eukaryotic cells
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| 650 |
2 |
2 |
|a Gene Expression Regulation
|
| 700 |
1 |
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|a Wu, Jane ,
|e author
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| 999 |
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|a 1000160266
|b Book
|c OPEN SHELF (30 DAYS)
|e Medical Campus
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