Chitosan-based systems for biopharmaceuticals : delivery, targeting, and polymer therapeutics

Bibliographic Details
Main Authors: Neves, Jose das , 1978- (Author), Sarmento, Bruno (Author)
Format: Book
Language:English
Published: Chichester, West Sussex : John Wiley & Sons , c2012
Subjects:
Table of Contents:
  • 1. Chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals
  • 2. Physical properties of chitosan and derivatives in sol and gel states
  • 3. Absorption promotion properties of chitosan and derivatives
  • 4. Biocompatibility and biodegradation of chitosan and derivatives
  • 5. Biological and pharmacological activity of chitosan and derivatives
  • 6. Biological, chemical, and physical compatibility of chitosan and biopharmaceuticals
  • 7. Approaches for functional modification or crosslinking of chitosan
  • 8. Use of chitosan and derivatives in conventional biopharmaceutical dosage forms formulation
  • 9. Manufacture techniques of chitosan-based micro particles and nanoparticles for biopharmaceuticals
  • 10. Chitosan and derivatives for biopharmaceutical use : mucoadhesive properties
  • 11. Chitosan-based systems for mucosal delivery of biopharmaceuticals
  • 12. Chitosan-based delivery systems for mucosal vaccination
  • 13. Chitosan-based Nano particulates for oral delivery of biopharmaceuticals
  • 14. Chitosan-based systems for ocular delivery of biopharmaceuticals
  • 15. Chemical modification of chitosan for delivery of DNA and SIRNA
  • 16. Target-specific chitosan-based nanoparticle systems for nucleic acid delivery
  • 17. Functional PEGylated chitosan systems for biopharmaceuticals
  • 18. Stimuli-sensitive chitosan-based systems for biopharmaceuticals
  • 19. Chitosan copolymers for biopharmaceuticals
  • 20. Application of chitosan for anti-cancer biopharmaceutical delivery
  • 21. Chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine
  • 22. Wound healing properties of chitosan and its use in wound dressing biopharmaceuticals
  • 23. Toxicological properties of chitosan and derivatives for biopharmaceutical applications
  • 24. Regulatory status of chitosan and derivatives
  • 25. Patentability and intellectual property issues related with chitosan-based biopharmaceutical products
  • 26. Quality control and good manufacturing practice (GMP) for chitosan-based biopharmaceutical products
  • 27. Preclinical and clinical use of chitosan and derivatives for biopharmaceuticals : from preclinical research to the bedside