Comprehensive chiroptical spectroscopy : applications in stereochemical analysis of synthetic compounds, natural products, and biomolecules
This book introduces the important methods of chiroptical spectroscopy in general, and circular dichroism (CD) in particular, which are increasingly important in chemistry, biochemistry, and structural biology. It functions well as an undergraduate and graduate text, and as a research reference, wit...
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| Format: | Book |
| Language: | English |
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Hoboken, New Jersey :
John Wiley & Sons ,
c2012
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Table of Contents:
- 1. The first decades after the discovery of cd and ord by aime cotton in 1895
- 2. Some inherently chiral chromophores-empirical rules and quantum chemical calculations
- 3. Electronic cd of benzene and other aromatic chromophores for determination of absolute configuration
- 4. Electronic cd exciton chirality method: principles and applications
- 5. Cd spectra of chiral extended p -electron compounds: theoretical determination of the absolute stereochemistry and experimental verification
- 6. Assignment of the absolute configurations of natural products by means of solid-state electronic circular dichroism and quantum mechanical calculations
- 7. Dynamic stereochemistry and chiroptical spectroscopy of metallo-organic compounds
- 8. Circular dichroism of dynamic systems: switching molecular and supramolecular chirality
- 9. Electronic circular dichroism of supramolecular systems
- 10. The online stereochemical analysis of chiral compounds by HPLC-ECD coupling in combination with quantum-chemical calculations
- 11. Determination of the structures of chiral natural products using vibrational circular dichroism
- 12. Determination of molecular absolute configuration: guidelines for selecting a suitable chiroptical approach
- 13. Applications of electronic circular dichroism to inorganic stereochemistry
- 14. Electronic circular dichroism of proteins
- 15. Electronic circular dichroism of peptides
- 16. Electronic circular dichroism of peptidomimetics
- 17. Circular dichroism spectroscopy of nucleic acids
- 18. Electronic circular dichroism of peptide nucleic acids and their analogues
- 19. Circular dichroism of protein-nucleic acid interactions
- 20. Drug and natural product binding to nucleic acids analyzed by electronic circular dichroism
- 21. Probing HSA and AGP drug-binding sites by electronic circular dichroism
- 22. Conformational studies of biopolymers, peptides, proteins, and nucleic acids. A role for vibrational circular dichroism
- 23. Structure and behavior of biomolecules from raman optical activity
- 24. Optical rotation, electronic circular dichroism, and vibrational circular dichroism of carbohydrates and glycoconjugates
- 25. Electronic circular dichroism in drug discovery