Introduction to proteins : structure, function, and motion

"The book aims to provide the reader with a detailed description of protein structure and dynamics, combined with an in-depth discussion of the relationship between both these aspects and protein function. Adopting the structural-biophysical approach, we discuss these in relation to molecular i...

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Bibliographic Details
Main Authors: Kessel, Amit (Author), Ben-Tal, Nir (Author)
Format: Book
Language:English
Published: Boca Raton, Florida : CRC Press/Taylor & Francis Group , c2011
Series:Chapman & Hall/CRC mathematical and computational biology series
Subjects:

MARC

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005 20110727.0
008 110522s2011 flu eng
020 |a 1439810710 (hardcover : alk. paper) 
020 |a 9781439810712 (hardcover : alk. paper) 
050 0 0 |a QP551   |b .K47 2011 
060 1 0 |a QU 55   |b K24 2011 
090 0 0 |a QP551   |b .K47 2011 
100 1 |a Kessel, Amit ,   |e author 
245 1 0 |a Introduction to proteins :   |b structure, function, and motion   |c Amit Kessel and Nir Ben-Tal 
260 |a Boca Raton, Florida :   |b CRC Press/Taylor & Francis Group ,   |c c2011 
300 |a xxvii, 626 p. :   |b ill. (chiefly col.) ;   |c 26 cm. 
440 0 |a Chapman & Hall/CRC mathematical and computational biology series 
490 1 |a Chapman & Hall/CRC mathematical and computational biology series 
504 |a Includes bibliographical references and index 
505 0 |a 1. Introduction -- 2. Protein structure -- 3. Methods of structure determination and prediction -- 4. Energetics and protein stability -- 5. Protein structural dynamics -- 6. Non-globular proteins -- 7. Membrane proteins -- 8. Protein-ligand interactions 
520 |a "The book aims to provide the reader with a detailed description of protein structure and dynamics, combined with an in-depth discussion of the relationship between both these aspects and protein function. Adopting the structural-biophysical approach, we discuss these in relation to molecular interactions and thermodynamic changes that transpire in this highly complex system. There are several types of textbooks describing protein structure and function. Biochemistry textbooks emphasize the functional aspect of proteins and provide a rather general description of structure and structure-function relationship (SFR). Structural Biology textbooks provide an extensive description of protein structure and also refer to SFR with varying degrees of detail. However, energy-related aspects are often avoided. Molecular biophysics textbooks focus on molecular interactions and thermodynamic aspects of protein structure, but tend to lack detailed description of structural and dynamic aspects, as well as SFR. Our book refers to all of the aforementioned aspects and attempts to provide a unified view. Our energy-oriented approach is manifested throughout the book, whether we discuss structure, dynamics or specific functions of proteins. An extensive discussion of the energetics of protein structure is also given in a chapter dedicated to this topic"--Provided by publisher 
650 0 |a Physical biochemistry 
650 0 |a Proteins 
650 0 |a Proteins   |x Structure-activity relationships 
650 1 2 |a Proteins   |x physiology 
650 2 2 |a Amino Acid Sequence 
650 2 2 |a Protein Conformation 
700 1 |a Ben-Tal, Nir ,   |e author 
999 |a 1000139693   |b Book   |c OPEN SHELF (30 DAYS)   |e Tembila Campus