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00000cam a2200000 7i4500 |
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20110106093000.0 |
| 008 |
101216s2000 nyu eng |
| 020 |
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|a 0824775724 (pbk.)
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| 050 |
0 |
0 |
|a RM301.6
|b .C46 2009
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| 060 |
1 |
0 |
|a QV 38
|b C552d 2009
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| 090 |
0 |
0 |
|a QV 38
|b C552d 2009
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| 100 |
1 |
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|a Chow, Shein-Chung ,
|d 1955- ,
|e author
|
| 245 |
1 |
0 |
|a Design and analysis of bioavailability and bioequivalence studies
|c Shein-Chung Chow, Jen-pei Liu
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| 250 |
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|a 2nd ed. revised and expanded
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| 260 |
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|a New York :
|b Marcel Dekker ,
|c c2000
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| 300 |
|
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|a xii, 584 p. ;
|c 26 cm.
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| 504 |
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|a Includes bibliographical references (p. 521-535) and index
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| 505 |
0 |
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|a 1. Introduction -- 2. Designs of bioavailability studies -- 3. Statistical inferences for effects from a standard 2x2 crossover design -- 4. Statistical methods for average bioavailability -- 5. Power and sample size determination -- 6. Transformation and analysis of individual subjects rations -- 7. The assessment of inter and intrasubject variabilities -- 8. Assumptions and outliers detection -- 9. Optimal crossover designs for two formulations -- 10. Assessment of bioequivalence for more than two formulations -- 11. Assessment of bioequivalence for drugs with negligible plasma levels -- 12. Some related problems in bioavailability studies -- 13. Meta-Analysis for bioequivalence review -- 14. Population and individual bioequivalence -- 15. Statistical procedures for assessment of population and individual bioequivalence -- 16. Review of FDA guidances
|
| 650 |
|
0 |
|a Bioavailability
|x Research
|x Statistical methods
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| 650 |
|
0 |
|a Drugs
|x Therapeutic equivalency
|x Research
|x Statistical methods
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| 650 |
1 |
2 |
|a Biological Availability
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| 650 |
2 |
2 |
|a Statistics as Topic
|x methods
|
| 650 |
2 |
2 |
|a Therapeutic Equivalency
|
| 700 |
1 |
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|a Liu, Jen-pei ,
|d 1952- ,
|e author
|
| 999 |
|
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|a 1000135523
|b Book
|c Open Shelf (1 Day)
|e Medical Campus
|