An investigation of the clinical relevance of genetic polymorphism of CYP2D6 in the use of tramadol hydrochloride in post operative orthopaedic patients

An investigation of the clinical relevance of genetic polymorphism of CYP2D6 in the use of tramadol hydrochloride in post operative orthopaedic patients

Despite recent advances in anaesthesia, postoperative analgesia remains inadequate and is governed by many factors, one of which is pharmacogenetics. Fear of drug dependence exists with conventional opioid analgesics and there are needs for new drugs such as tramadol hydrochloride. Tramadol however,...

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Bibliographic Details
Main Author: Gan, Siew Hua (Author)
Corporate Author: Universiti Sains Malaysia . Pusat Pengajian Sains Farmasi
Format: Thesis Book
Language:English
Subjects:
Universiti Sains Malaysia > Dissertations
Analgesics
Cyctochrome P-450
Genetic polymorphisms
Polymorphism, Genetic
Postoperative pain > Drug therapy
Tramadol CYP2D6
Academic Dissertations

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